abstract |
1,3-substituted cycloalkenes and cycloalkanes of Formula (I): Z-CH2?-Y wherein Z is (a), (b), (c) or (d), Y is (e) or (f) wherein the meanings of R and m are provided in the description, are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as dopaminergic, antipsychotic, and antihypertensive agents as well as for treating hyperprolactinaemia-related conditions and central nervous system desorders. |