| abstract |
Antiviral nucleoside analogues contain a substituted benzimidazole base attached to a carbocyclic ring in a place of the conventional sugar residue. Particularly preferred compounds include those in which the 2-,5- and 6- positions of the benzimidazole base are substituted by halogen. The compounds have activity against herpes virus especially cytomegalovirus and also hepatitis B virus infections. |