http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9509833-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53dff29241864c5dc0eeca3fcbe40674 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54 |
| filingDate | 1994-10-03^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d07021e3000b8d752682eb5214cf170 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4abcd6a6cc87b044d518e1f078b5c40a |
| publicationDate | 1995-04-13^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-9509833-A1 |
| titleOfInvention | Mercaptosulfide metalloproteinase inhibitors |
| abstract | Novel mercaptosulfide matrix metalloproteinase inhibitors of formula (I), wherein n is 0 or 1; R<1> is selected from the group consisting of hydrogen, lower alkyl, amino lower alkyl, carbamoyl lower alkyl, PhtN (lower alkyl), TsNH (lower alkyl); and R<2> is selected from the group consisting of hydrogen, lower alkyl, amino lower alkyl, carbamoyl lower alkyl, PhtN (lower alkyl), TsNH (lower alkyl); or R<1> and R<2> together are -CH2-CH2-CH2-; R<3> is selected from the group consisting of hydrogen, lower alkyl, aralkyl and heteroaralkyl; and R<4> is selected from the group consisting of hydrogen, lower alkyl, amino lower-alkyl, guanyl lower-alkyl, imidazoylalkyl, aralkyl and 2-indolylmethyl; and R<5> is selected from the group consisting of lower alkyl, aralkyl and -CH(R<6>)-C(O)NH2, wherein R<6> is selected from the group consisting of hydrogen, lower-alkyl, amino lower-alkyl, guanyl lower-alkyl, imidazoylalkyl, hydroxymethyl, 1-hydroxyethyl, mercapto lower-alkyl, and methylthio lower-alkyl; or a pharmaceutically acceptable ester, ether or salt thereof, useful for treating diseases and disease conditions associated with matrix metalloproteinase modulation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9725981-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5852213-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9907679-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6124502-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5716979-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5594022-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5955435-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6121272-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9806696-A1 |
| priorityDate | 1993-10-06^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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