| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_81ba2c4156354c844d4a8883be561f00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L15-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 |
| filingDate |
1995-07-18^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63ad3528cb5cfa695ee9b282d414778d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_106365cb483180bda9f2a48d5b9138eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_108e5f57579f54ed77a472f837482f77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e22564a30bd0337d0926e32868fe778
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e25f2ef13b8dea0b1b91ed92247a0eaa |
| publicationDate |
1996-02-01^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-9602239-A2 |
| titleOfInvention |
Enhanced loading of solutes into polymer gels and methods of use |
| abstract |
A method of loading a drug into a crosslinked polymer network and protecting the drug from the effects of inactivation is described. The method includes the steps of contacting of a biologically active solute (i.e., drug) with: (i) a gel network; (ii) a second protectant polymer that is somewhat immiscible with the gel; and (iii) a protectant salt, under conditions sufficient for the biologically active solute to selectively partition into the gel and the protectants to be entrained in the gel. A drug delivery system is also described. It comprises a polymer gel network including the drug to be delivered; protectants including a salt and a loading polymer, the salt and the loading polymer capable of protecting the drug from loss of activity. The polymer gel network is capable of expanding or collapsing in response to a change in an environmental condition to which the gel is exposed, the expanding or collapsing sufficient to release the drug into an environment of use. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6242002-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-65043-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6649190-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9822093-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0842657-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11419329-B2 |
| priorityDate |
1994-07-18^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |