abstract |
The invention concerns hydroxamic acid and carboxylic acid derivatives of formulae (I): B-X-(CH2)n-CHR1-(CH2)m-CONHOH and (Ia): B-S(O)1-2-(CH2)n-CHR1-(CH2)m-COOR2, in which X is O, NR¿3? or S(O)0-2, and the other variables have the definitions given in the claims, having MMP and TNF inhibitory activity. |