| abstract |
A novel cyclodepsipeptide derivative of formula (I) wherein (i) R1 is hydrogen atom and R2 is a substituted 2-furylmethoxy group, a 3-furylmethoxy group or a 2-thienylmethoxy group, or (ii) both of R1 and R2 are each a 2-furylmethoxy group, a 2-thienylmethoxy group or others, is now provided by chemical syntheses from the fermentatively producible, known PF1022 E or PF1022 H substance. The novel cyclodepsipeptides have excellent and unique anthelmintic activities against parasites of animals and humans. |