| abstract |
The invention concerns a method for preparing 2-aryl or 2-heterocyclyl chiral propionic acids and their esters by electrochemical reduction of a mixture of a propionic acid derivative of formula (II) in which R3 represents a radical of formula (A), (B), (C) and Hal represents a halogen atom and an aromatic or heterocyclic halogen derivative, in the presence of a nickel complex as catalyst and an electrolyte, then either by hydrolysis to obtain the propionic acid derivative or by transesterification to obtain the ester. |