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Pindrus M, Shire SJ, Kelley RF, Demeule B, Wong R, Xu Y, Yadav S. Solubility Challenges in High Concentration Monoclonal Antibody Formulations: Relationship with Amino Acid Sequence and Intermolecular Interactions. Mol Pharm. 2015 Nov 02;12(11):3896–907. doi: 10.1021/acs.molpharmaceut.5b00336. PMID: 26407030. |