TJAP1

TJAP1
Identifikatori
Aliasi	TJAP1
Vanjski ID-jevi	OMIM: 612658 MGI: 1921344 HomoloGene: 12534 GeneCards: TJAP1
Lokacija gena (čovjek)
Hrom.	Hromosom 6 (čovjek)
Kraj	43,506,556 bp
Lokacija gena (miš)
Hrom.	Hromosom 17 (miš)
Kraj	46,593,952 bp
Obrazac RNK ekspresije
	; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• citoplazma; • međućelijske veze; • endozom; • trans-Golđijeva mreža; • ćelijska membrana; • bicellular tight junction; • Golđijev aparat;
Biološki proces	• Golgi organization;
	Izvori:Amigo / QuickGO
Ortolozi
	93643
	74094
	ENSG00000137221
	ENSMUSG00000012296
	Q5JTD0
	Q9DCD5
NM_001146016; NM_001146017; NM_001146018; NM_001146019; NM_001146020;
	NM_080604; NM_001350561; NM_001350562; NM_001350563; NM_001350564; NM_001350565; NM_001350566; NM_001350567; NM_001350568; NM_001350569; NM_001350570; NM_001394538; NM_001394539; NM_001394540; NM_001394541; NM_001394542; NM_001394543; NM_001394544; NM_001394545
	NM_001252473; NM_001252474; NM_001252475; NM_028751
NP_001139488; NP_001139489; NP_001139490; NP_001139491; NP_001139492;
	NP_542171; NP_001337490; NP_001337491; NP_001337492; NP_001337493; NP_001337494; NP_001337495; NP_001337496; NP_001337497; NP_001337498; NP_001337499
	NP_001239402; NP_001239403; NP_001239404; NP_083027
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Uskovezno pridruženi protein 1 jest protein koji je kod ljudi kodiran genom TJAP1.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 557 aminokiselina, а molekulska težina 61.821 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MTSAAPAKKP	YRKAPPEHRE	LRLEIPGSRL	EQEEPLTDAE	RMKLLQEENE
ELRRRLASAT	RRTEALEREL	EIGQDCLELE	LGQSREELDK	FKDKFRRLQN
SYTASQRTNQ	ELEDKLHTLA	SLSHSWIFAI	KKAEMDRKTL	DWEIVELTNK
LLDAKNTINK	LEELNERYRL	DCNLAVQLLK	CNKSHFRNHK	FADLPCELQD
MVRKHLHSGQ	EAASPGPAPS	LAPGAVVPTS	VIARVLEKPE	SLLLNSAQSG
SAGRPLAEDV	FVHVDMSEGV	PGDPASPPAP	GSPTPQPNGE	CHSLGTARGS
PEEELPLPAF	EKLNPYPTPS	PPHPLYPGRR	VIEFSEDKVR	IPRNSPLPNC
TYATRQAISL	SLVEEGSERA	RPSPVPSTPA	SAQASPHHQP	SPAPLTLSAP
ASSASSEEDL	LVSWQRAFVD	RTPPPAAVAQ	RTAFGRDALP	ELQRHFAHSP
ADRDEVVQAP	SARPEESELL	LPTEPDSGFP	REEEELNLPI	SPEEERQSLL
PINRGTEEGP	GTSHTEGRAW	PLPSSSRPQR	SPKRMGVHHL	HRKDSLTQAQ
EQGNLLN

Interakcije

Pokazano je da TJAP1 ima interakcije sa DLG1.^[5]

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137221 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000012296 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Kawabe H, Nakanishi H, Asada M, Fukuhara A, Morimoto K, Takeuchi M, Takai Y (Dec 2001). "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells". J Biol Chem. 276 (51): 48350–5. doi:10.1074/jbc.M107335200. PMID 11602598.
^ "Entrez Gene: TJAP1 tight junction associated protein 1 (peripheral)".
^ "UniProt, Q5JTD0" (jezik: engleski). Pristupljeno 5. 10. 2021.

Dopunska literatura

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Xavier R, Rabizadeh S, Ishiguro K, et al. (2004). "Discs large (Dlg1) complexes in lymphocyte activation". J. Cell Biol. 166 (2): 173–8. doi:10.1083/jcb.200309044. PMC 2172307. PMID 15263016.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000137221 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000012296 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11602598-5] Kawabe H, Nakanishi H, Asada M, Fukuhara A, Morimoto K, Takeuchi M, Takai Y (Dec 2001). "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells". J Biol Chem. 276 (51): 48350–5. doi:10.1074/jbc.M107335200. PMID 11602598.

[entrez-6] "Entrez Gene: TJAP1 tight junction associated protein 1 (peripheral)".

[UniProt-7] "UniProt, Q5JTD0" (jezik: engleski). Pristupljeno 5. 10. 2021.

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