About: Apricitabine

Property	Value
dbo:abstract	Apricitabin (SPD754, AVX754) ist ein experimenteller Arzneistoff zur Behandlung von HIV-infizierten Patienten im Rahmen einer HIV-Kombinationstherapie. Er gehört zur Gruppe der nukelosidischen Reverse-Transkriptase-Inhibitoren (NRTI). (de) Apricitabine (INN, codenamed AVX754 and SPD754, sometimes abbreviated to ATC) is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV. It is structurally related to lamivudine and emtricitabine, and, like these, is an analogue of cytidine. (en)
dbo:bioavailability	65.000000 (xsd:float)
dbo:casNumber	160707-69-7
dbo:chEMBL	210651
dbo:fdaUniiCode	K1YX059ML1
dbo:pubchem	455041
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dbp:atcPrefix	none (en)
dbp:bioavailability	65 (xsd:integer)
dbp:c	8 (xsd:integer)
dbp:casNumber	160707 (xsd:integer)
dbp:chembl	210651 (xsd:integer)
dbp:chemspiderid	400685 (xsd:integer)
dbp:eliminationHalfLife	25200.0 (dbd:second)
dbp:excretion	dbr:Kidney
dbp:h	11 (xsd:integer)
dbp:iupacName	4 (xsd:integer)
dbp:legalStatus	Investigational (en)
dbp:metabolism	To apricitabine triphosphate (en)
dbp:n	3 (xsd:integer)
dbp:o	3 (xsd:integer)
dbp:proteinBound	< 4% (en)
dbp:pubchem	455041 (xsd:integer)
dbp:routesOfAdministration	Oral (en)
dbp:s	1 (xsd:integer)
dbp:smiles	O=C1/N=C\C=C/N1[C@@H]2S[C@@H]CO (en)
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dbp:unii	K1YX059ML1 (en)
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gold:hypernym	dbr:Inhibitor
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rdfs:comment	Apricitabin (SPD754, AVX754) ist ein experimenteller Arzneistoff zur Behandlung von HIV-infizierten Patienten im Rahmen einer HIV-Kombinationstherapie. Er gehört zur Gruppe der nukelosidischen Reverse-Transkriptase-Inhibitoren (NRTI). (de) Apricitabine (INN, codenamed AVX754 and SPD754, sometimes abbreviated to ATC) is an experimental nucleoside reverse transcriptase inhibitor (NRTI) against HIV. It is structurally related to lamivudine and emtricitabine, and, like these, is an analogue of cytidine. (en)
rdfs:label	Apricitabin (de) Apricitabine (en)
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