About: Cyclofenil

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Cyclofenil, sold under the brand name Sexovid among others, is a selective estrogen receptor modulator (SERM) medication which is used as a gonadotropin stimulant or ovulation inducer and in menopausal hormone therapy in women. It is mostly no longer available. The medication is taken by mouth. Cyclofenil was introduced for medical use in 1970. It has been mostly discontinued, but remains available in a few countries, including Brazil, Italy, and Japan. It has been used as a doping agent by male athletes.

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  • Cyclofenil, sold under the brand name Sexovid among others, is a selective estrogen receptor modulator (SERM) medication which is used as a gonadotropin stimulant or ovulation inducer and in menopausal hormone therapy in women. It is mostly no longer available. The medication is taken by mouth. Side effects of cyclofenil include liver toxicity among others. It is a selective estrogen receptor modulator (SERM) and hence is a mixed agonist–antagonist of the estrogen receptor (ER), the biological target of estrogens like estradiol. It has antiestrogenic effects on the hypothalamic–pituitary–gonadal axis and hence can increase sex hormone production and stimulate ovulation. Cyclofenil was introduced for medical use in 1970. It has been mostly discontinued, but remains available in a few countries, including Brazil, Italy, and Japan. It has been used as a doping agent by male athletes. (en)
dbo:alternativeName
  • Sexovid, others (en)
dbo:casNumber
  • 2624-43-3
dbo:chEMBL
  • 141305
dbo:class
dbo:fdaUniiCode
  • J468V64WZ1
dbo:kegg
  • D01281
dbo:pubchem
  • 2898
dbo:thumbnail
dbo:wikiPageID
  • 20007024 (xsd:integer)
dbo:wikiPageLength
  • 13616 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1104163379 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • G03 (en)
dbp:atcSuffix
  • GB01 (en)
dbp:c
  • 23 (xsd:integer)
dbp:casNumber
  • 2624 (xsd:integer)
dbp:chembl
  • 141305 (xsd:integer)
dbp:chemspiderid
  • 2795 (xsd:integer)
dbp:class
dbp:eliminationHalfLife
  • -104400.0 (dbd:second)
dbp:h
  • 24 (xsd:integer)
dbp:iupacName
  • [4-[-cyclohexylidene-methyl]phenyl] acetate (en)
dbp:kegg
  • D01281 (en)
dbp:o
  • 4 (xsd:integer)
dbp:pubchem
  • 2898 (xsd:integer)
dbp:routesOfAdministration
dbp:smiles
  • O=CC (en)
dbp:synonyms
  • Cyclophenil; F-6066; H-3452; ICI-48213; bis-cyclohexylidenemethane (en)
dbp:tradename
  • Sexovid, others (en)
dbp:unii
  • J468V64WZ1 (en)
dbp:width
  • 250 (xsd:integer)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:comment
  • Cyclofenil, sold under the brand name Sexovid among others, is a selective estrogen receptor modulator (SERM) medication which is used as a gonadotropin stimulant or ovulation inducer and in menopausal hormone therapy in women. It is mostly no longer available. The medication is taken by mouth. Cyclofenil was introduced for medical use in 1970. It has been mostly discontinued, but remains available in a few countries, including Brazil, Italy, and Japan. It has been used as a doping agent by male athletes. (en)
rdfs:label
  • Cyclofenil (en)
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owl:sameAs
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foaf:isPrimaryTopicOf
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is foaf:primaryTopic of
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