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In biochemistry, equilibrium unfolding is the process of unfolding a protein or RNA molecule by gradually changing its environment, such as by changing the temperature or pressure, pH, adding chemical denaturants, or applying force as with an atomic force microscope tip. If the equilibrium was maintained at all steps, the process theoretically should be reversible during equilibrium folding. Equilibrium unfolding can be used to determine the thermodynamic stability of the protein or RNA structure, i.e. free energy difference between the folded and unfolded states.

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  • In biochemistry, equilibrium unfolding is the process of unfolding a protein or RNA molecule by gradually changing its environment, such as by changing the temperature or pressure, pH, adding chemical denaturants, or applying force as with an atomic force microscope tip. If the equilibrium was maintained at all steps, the process theoretically should be reversible during equilibrium folding. Equilibrium unfolding can be used to determine the thermodynamic stability of the protein or RNA structure, i.e. free energy difference between the folded and unfolded states. (en)
  • En bioquímica, el desarrollo de equilibrio es el proceso de desplegar una molécula de proteína o ARN al cambiar gradualmente su entorno, como al cambiar la temperatura o la presión, agregar desnaturalizantes químicos o aplicar fuerza como con una punta de microscopio de fuerza atómica. Dado que el equilibrio se mantiene en todos los pasos, el proceso es reversible (plegamiento de equilibrio). El despliegue de equilibrio se utiliza para determinar la estabilidad conformacional de la molécula. (es)
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  • In biochemistry, equilibrium unfolding is the process of unfolding a protein or RNA molecule by gradually changing its environment, such as by changing the temperature or pressure, pH, adding chemical denaturants, or applying force as with an atomic force microscope tip. If the equilibrium was maintained at all steps, the process theoretically should be reversible during equilibrium folding. Equilibrium unfolding can be used to determine the thermodynamic stability of the protein or RNA structure, i.e. free energy difference between the folded and unfolded states. (en)
  • En bioquímica, el desarrollo de equilibrio es el proceso de desplegar una molécula de proteína o ARN al cambiar gradualmente su entorno, como al cambiar la temperatura o la presión, agregar desnaturalizantes químicos o aplicar fuerza como con una punta de microscopio de fuerza atómica. Dado que el equilibrio se mantiene en todos los pasos, el proceso es reversible (plegamiento de equilibrio). El despliegue de equilibrio se utiliza para determinar la estabilidad conformacional de la molécula. (es)
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  • Desarrollo de equilibrio (es)
  • Equilibrium unfolding (en)
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