St. Charles College was a private Jesuit college in Grand Coteau, Louisiana. Founded in 1837 by Jesuits from France and Kentucky, the school was the first Jesuit college established in the American South. It initially educated lay students exclusively until 1890, when it began functioning as a Jesuit scholasticate as well. In 1922, the college closed, and the campus was used only to train Jesuit novices. Today, the campus continues to be used for the training of Jesuits, as well as a retreat center and a home for elderly Jesuits. The surviving structures date to 1909 and are contributing properties of the .