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- The transforming growth factor beta (TGF-β) superfamily is a large group of structurally related cell regulatory proteins that was named after its first member, TGF-β1, originally described in 1983. They interact with TGF-beta receptors. Many proteins have since been described as members of the TGF-β superfamily in a variety of species, including invertebrates as well as vertebrates and categorized into 23 distinct gene types that fall into four major subfamilies:
* The TGF-β subfamily
* The bone morphogenetic proteins and the growth differentiation factors
* The activin and inhibin subfamilies
* The left-right determination factors
* A group encompassing various divergent members Transforming growth factor-beta (TGF-beta) is a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. TGF-beta-1 is a peptide of 112 amino acid residues derived by proteolytic cleavage from the C-terminal of a precursor protein. These proteins interact with a conserved family of cell surface serine/threonine-specific protein kinase receptors, and generate intracellular signals using a conserved family of proteins called SMADs. They play fundamental roles in the regulation of basic biological processes such as growth, development, tissue homeostasis and regulation of the immune system. (en)
- 转化生长因子-β超家族（transforming growth factor beta superfamily，TGF-β superfamily）是生长因子中的一大家族。分为多个亚家族：
* 转化生长因子-β亚家族，包括：、、
* DVR（decapentaplegic Vg-related）亚家族，包括：
* 骨塑型蛋白（BMPs），如：、、、
* （GDFs），如：生长分化因子1－3、生长分化因子5－11、生长分化因子15
* 激活素与抑制素，如：激活素A、激活素B、抑制素A、抑制素B
* 其他，如：Nodal (zh)
- Суперсемейство трансформирующего ростового фактора Beta (ТРФ-B) — большое семейство структурно связанных регуляторных белков, которое было названо по его первому члену, ТРФ-B1, впервые описанном в 1983 году. (ru)
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- 6716 (xsd:nonNegativeInteger)
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- Structure of human transforming growth factor-beta 2. (en)
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- Transforming growth factor beta like domain (en)
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- 转化生长因子-β超家族（transforming growth factor beta superfamily，TGF-β superfamily）是生长因子中的一大家族。分为多个亚家族：
* 转化生长因子-β亚家族，包括：、、
* DVR（decapentaplegic Vg-related）亚家族，包括：
* 骨塑型蛋白（BMPs），如：、、、
* （GDFs），如：生长分化因子1－3、生长分化因子5－11、生长分化因子15
* 激活素与抑制素，如：激活素A、激活素B、抑制素A、抑制素B
* 其他，如：Nodal (zh)
- Суперсемейство трансформирующего ростового фактора Beta (ТРФ-B) — большое семейство структурно связанных регуляторных белков, которое было названо по его первому члену, ТРФ-B1, впервые описанном в 1983 году. (ru)
- The transforming growth factor beta (TGF-β) superfamily is a large group of structurally related cell regulatory proteins that was named after its first member, TGF-β1, originally described in 1983. They interact with TGF-beta receptors. Many proteins have since been described as members of the TGF-β superfamily in a variety of species, including invertebrates as well as vertebrates and categorized into 23 distinct gene types that fall into four major subfamilies: (en)
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- Transforming growth factor beta superfamily (en)
- Суперсемейство трансформирующего ростового фактора-бета (ru)
- 转化生长因子-β超家族 (zh)
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