Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets
Fig 3
Characteristics of chosen regions.
Conservation, chromatin events and TF binding events in chosen CREs (red) compared to all candidate CREs (blue). Left is the TF gene set, middle the TF cluster set and right all differentially expressed genes (DE set). (A) The log of the phylogenetic conservation scores (see Methods), (B) the chromatin events (H3K27Ac peaks and DHS), and (C) TF binding events. The p values were obtained using student t-test for conservation and Kolmogorov-Smirnoff test for chromatin and binding events. All the p values were less than 0.01 except for conservation distribution in TF set (p = 0.07).
