Biotin hydrazide

Biotin hydrazide
Names
	Preferred IUPAC name 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanehydrazide
	Other names (+)-Biotin hydrazide
Identifiers
CAS Number	66640-86-6;
3D model (JSmol)	Interactive image;
ECHA InfoCard	100.110.982
PubChem CID	83872;
CompTox Dashboard (EPA)	DTXSID50985217 ;
	InChI InChI=1S/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1 Key: KOZWHQPRAOJMBN-ZKWXMUAHSA-N;
	SMILES C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NN)NC(=O)N2;
Properties
Chemical formula	C10H18N4O2S
Molar mass	258.34 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Biotin hydrazide is a biotinyl derivative that can be used as a probe for the determination of protein carbonylation. It readily forms Schiff bases with carbonyl groups.^[1]

References

^ Madian, Ashraf G; Regnier, Fred E (2010). "Proteomic Identification of Carbonylated Proteins and Their Oxidation Sites". Journal of Proteome Research. 9 (8): 3766–80. doi:10.1021/pr1002609. PMC 3214645. PMID 20521848.

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[Madian-1] Madian, Ashraf G; Regnier, Fred E (2010). "Proteomic Identification of Carbonylated Proteins and Their Oxidation Sites". Journal of Proteome Research. 9 (8): 3766–80. doi:10.1021/pr1002609. PMC 3214645. PMID 20521848.

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