Europe PMC

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and cookie policy.

Nuclear chaperones.

Author information

Affiliations

  • 1. Department of Oncology, University of Cambridge, Wellcome Trust Centre for the Study of Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, Wellcome/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 2XY, UK.
      Authors
    • Philpott A 1
    (1 author)

ORCIDs linked to this article

Seminars in Cell & Developmental Biology, 01 Feb 2000, 11(1):7-14
https://doi.org/10.1006/scdb.1999.0346 PMID: 10736259 

Review

Abstract 

We discuss nuclear chaperones that bind correctly folded protein subunits and mediate molecular interactions, particularly between proteins and nucleic acids. The charge of these chaperones helps to prevent non-specific electrostatic interactions between the components. Thus, an ordered assembly of macromolecular complexes is mediated, most notably in the formation and maintenance of chromatin, though similar principles are likely to apply in ribonucleoprotein assembly. Here, we discuss roles for nuclear chaperones in mediating nucleosome assembly and remodelling during DNA replication and transcription, and upon fertilisation.

Full text links 

Read article at publisher's site: https://doi.org/10.1006/scdb.1999.0346

References 

Articles referenced by this article (73)

Show 10 more references (10 of 73)

Citations & impact 

Impact metrics

72
Citations
Jump to Citations
1
Data citation
Jump to Data

Citations of article over time

Alternative metrics

Altmetric item for https://www.altmetric.com/details/3557816
Altmetric
Discover the attention surrounding your research
https://www.altmetric.com/details/3557816

Article citations

Go to all (72) article citations

Other citations

Data 

Similar Articles 

To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.