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Inaccurate confidence intervals reported in "The Healthy Kids & Families Study: Outcomes of a 24-month Childhood Obesity Prevention Intervention".

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Affiliations

  • 1. Department of Epidemiology and Biostatistics, School of Public Health, Indiana University - Bloomington, Bloomington, IN, USA.
      Authors
    • Li X 1
    • Siddique AB 1
    • Golzarri-Arroyo L 1
    • Dickinson SL 1
    • Allison DB 1
    (5 authors)
  • 2. ConscienHealth, Pittsburgh, PA, USA.
      Authors
    • Kyle TK 2
    (1 author)

ORCIDs linked to this article

Preventive Medicine Reports, 27 Jul 2023, 35:102338
https://doi.org/10.1016/j.pmedr.2023.102338 PMID: 37752981 PMCID: PMC10518788

This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
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Logo of pmedrLink to Publisher's site
Prev Med Rep. 2023 Oct; 35: 102338.
Published online 2023 Jul 27. https://doi.org/10.1016/j.pmedr.2023.102338
PMCID: PMC10518788
PMID: 37752981

Inaccurate confidence intervals reported in “The Healthy Kids & Families Study: Outcomes of a 24-month Childhood Obesity Prevention Intervention”

Xingsheng Li,[low asterisk] Abu Bakkar Siddique, Lilian Golzarri-Arroyo, and Stephanie L. Dickinson
Department of Epidemiology and Biostatistics, School of Public Health, Indiana University - Bloomington, Bloomington, IN, USA
Theodore K. Kyle
ConscienHealth, Pittsburgh, PA, USA
David B. Allison
Department of Epidemiology and Biostatistics, School of Public Health, Indiana University - Bloomington, Bloomington, IN, USA
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Associated Data

Data Availability Statement

We reviewed the 2023 paper by Rosal et al. (2023) with interest, which reported that The Healthy Kids & Families intervention showed “promise” for obesity prevention among children in disadvantaged socioeconomic communities. We found inaccurate numerical results and discrepancies which should be corrected.

The point estimate for the intervention associated with the primary outcome of change in BMI z-scores is reported in the abstract as β = −0.17, with a 95 % confidence interval (CI) of −1.92 to −0.36 and p = 0.057. This cannot be correct because the point estimate does not lie within the interval. The corresponding results for the intervention effect on BMI z-scores are reported in Table 2 as β = −0.17, 95 % CI (−0.36, 0.01), p = 0.059, but the CI and p-value do not match the abstract.

There is also an inconsistency in the point estimate for the secondary outcome of the number of positive behavior changes among children, which is reported as β = 0.57 (95 % CI:0.08–1.06, p = 0.02) in the abstract, but is shown as β = 0.61 (SE = 0.25) in Table 3.

Discrepancies and incorrect numerical results should be corrected.

Declaration of Competing Interest

In the last thirty-six months, D.B. Allison has received personal payments or promises for same from: Amin Talati Wasserman for KSF Acquisition Corp (Glanbia); General Mills; Gerson Lehman Group, Inc.; Kaleido Biosciences; Law Offices of Ronald Marron; Novo Nordisk Fonden; USDA Agricultural Research Service; and Zero Longevity Science (as stock options). Donations to a foundation have been made on his behalf by the Northarvest Bean Growers Association. T.K. Kyle has received personal payments for professional services or promises for same from: Boehringer Ingelheim, Emerald Lake Safety, Johnson & Johnson, Novo Nordisk, Nutrisystem, and Roman Health Ventures. X. Li, A.B. Siddique, L. Golzarri-Arroyo, S.L. Dickinson, and D.B. Allison’s institution, Indiana University, and the Indiana University Foundation have received funds or donations to support his research or educational activities from: Alliance for Potato Research and Education; American Egg Board; Arnold Ventures; Eli Lilly and Company; Mars, Inc.; National Cattlemen’s Beef Association; National Pork Board; Pfizer, Inc.; Soleno Therapeutics; WW (formerly Weight Watchers); and numerous other for-profit and non-profit organizations to support the work of the School of Public Health and the university more broadly.

Acknowledgments

The authors thank Anna Macagno and Colby Vorland for helpful discussions and support with this submission. This work was funded in part by the National Institutes of Health (NIH): R25HL124208, R25DK099080, and the Gordon and Betty Moore Foundation grant GBMF8747.01. The opinions expressed are those of the authors and not necessarily of the NIH or any other organization.

Data availability

Summary data were provided in Rosal et al. (2023). No individual-level data were needed for this Correspondence.

References

  • Rosal M.C., Lemon S.C., Borg A., Lopez-Cepero A., et al. The Healthy Kids & Families Study: Outcomes of a 24-month childhood obesity prevention intervention. Prev. Med. Rep. 2023;31 10.1016/j.pmedr.2022.102086. [Europe PMC free article] [Abstract] [CrossRef] [Google Scholar]
Articles from Preventive Medicine Reports are provided here courtesy of Elsevier

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Funding 

Funders who supported this work.

Gordon and Betty Moore Foundation (1)

National Institutes of Health (2)