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Double-stranded regions in heterogeneous nuclear RNA from Hela cells.

Proceedings of the National Academy of Sciences of the United States of America, 01 Sep 1972, 69(9):2537-2541
https://doi.org/10.1073/pnas.69.9.2537 PMID: 4506771 PMCID: PMC426983

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Abstract 

Heterogeneous nuclear RNA from HeLa cells contains double-stranded regions that arise by base pairing of complementary sequences that exist as parts of the same molecule (intramolecular base pairing). When denatured, the RNA sequences that form the double-stranded regions hybridize rapidly to HeLa cell DNA, suggesting that they are transcribed from reiterated sites in the genome. The messenger RNA does not contain the same class or amount of double-stranded RNA regions found in heterogeneous nuclear RNA.

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Proc Natl Acad Sci U S A. 1972 Sep; 69(9): 2537–2541.
PMCID: PMC426983
PMID: 4506771

Double-Stranded Regions in Heterogeneous Nuclear RNA from Hela Cells

Warren Jelinek and James E. Darnell
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Abstract

Heterogeneous nuclear RNA from HeLa cells contains double-stranded regions that arise by base pairing of complementary sequences that exist as parts of the same molecule (intramolecular base pairing). When denatured, the RNA sequences that form the double-stranded regions hybridize rapidly to HeLa cell DNA, suggesting that they are transcribed from reiterated sites in the genome. The messenger RNA does not contain the same class or amount of double-stranded RNA regions found in heterogeneous nuclear RNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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