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Methylation analysis on individual chromosomes: improved protocol for bisulphite genomic sequencing.

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  • 1. Laboratory of Developmental Genetics and Imprinting, AFRC Babraham Institute, Cambridge, UK.
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    • Feil R 1
    (1 author)

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Nucleic Acids Research, 01 Feb 1994, 22(4):695-696
https://doi.org/10.1093/nar/22.4.695 PMID: 8127720 PMCID: PMC307863

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Nucleic Acids Res. 1994 Feb 25; 22(4): 695–696.
PMCID: PMC307863
PMID: 8127720

Methylation analysis on individual chromosomes: improved protocol for bisulphite genomic sequencing.

R Feil, J Charlton, A P Bird, J Walter, and W Reik
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Abstract

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Selected References

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  • Hayatsu H, Wataya Y, Kai K, Iida S. Reaction of sodium bisulfite with uracil, cytosine, and their derivatives. Biochemistry. 1970 Jul 7;9(14):2858–2865. [Abstract] [Google Scholar]
  • Shapiro R, DiFate V, Welcher M. Deamination of cytosine derivatives by bisulfite. Mechanism of the reaction. J Am Chem Soc. 1974 Feb 6;96(3):906–912. [Abstract] [Google Scholar]
  • Hayatsu H. Bisulfite modification of nucleic acids and their constituents. Prog Nucleic Acid Res Mol Biol. 1976;16:75–124. [Abstract] [Google Scholar]
  • Shortle D, Nathans D. Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome. Proc Natl Acad Sci U S A. 1978 May;75(5):2170–2174. [Europe PMC free article] [Abstract] [Google Scholar]
  • Frommer M, McDonald LE, Millar DS, Collis CM, Watt F, Grigg GW, Molloy PL, Paul CL. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1827–1831. [Europe PMC free article] [Abstract] [Google Scholar]
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