PMC full text: | Published online 2024 Aug 30. doi: 10.3390/jcm13175146
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TWL ≥ 30% n: 109 (76.8%) | TWL < 30% n: 33 (23.2%) | ||
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Gender female, n (%) | 76 (69.7%) | 25 (75.8%) | 0.33 |
Age (y), mean ± SD | 45.2 ± 9.0 | 48.0 ± 9.8 | 0.12 |
Type of surgery, n (%) | RYGBP: 96 (88.1) SG: 13 (11.9) | RYGBP: 28 (84.8) SG: 5 (15.2) | 0.41 |
Basal BMI (kg/m2), median [IQR] | 43.93 [40.8–49.0] | 41.3 [39.5–44.5] | <0.01 |
Excess weight (kg), median [IQR] | 53 [40.3–65.7] | 43.8 [39.1–51.0] | <0.01 |
WHR, median [IQR] | 0.9 [0.9–1.0] | 0.9 [0.8–1.0] | 0.42 |
Diabetes mellitus, n (%) | 26 (23.9) | 12 (36.4) | 0.16 |
OSAS, n (%) | 45 (41.3) | 16 (48.5) | 0.38 |
CPAP, n (%) | 34 (31.2) | 11 (33.3) | 0.84 |
Hypertension, n (%) | 29 (26.6) | 10 (30.3) | 0.68 |
Serum morning cortisol (μg/dL), median [IQR] | 12.0 [8.7–16.6] | 12.5 [10.3–15.3] | 0.83 |
DST (cortisol, μg/dL), median [IQR] | 0.8 [0.6–1.0] | 0.8 [0.7–1.2] | 0.27 |
Delta cortisol (μg/dL), median [IQR] | 11.1 [8.0–15.6] | 12.0 [9.4–14.3] | 0.33 |
UFC (μg/24 h), median [IQR] | 45.6 [27.9–68.9] | 26.6 [17.6–52.9] | 0.46 |
LNSC (μg/dL), median [IQR] | 0.8 [0.5–1.5] | 0.6 [0.3–1.6] | 0.62 |
ESR (mm/h), mean ± SD | 43.3 ± 25.1 | 45.5 ± 25.3 | 0.65 |
IL-6 (pg/mL), mean ± SD | 5.0 ± 3.2 | 4.0 ± 1.9 | 0.40 |
SHBG (nmol/L), mean ± SD | 33.2 ± 20.0 | 34.1 ± 16.8 | 0.82 |
HOMA, mean ± SD | 6.6 ± 6.5 | 5.7 ± 3.8 | 0.28 |
Abbreviations: RYGBP: Roux-en-Y gastric bypass; SG: sleeve gastrectomy; BMI: body mass index; OSAS: obstructive sleep apnea syndrome; CPAP: continuous positive airway pressure; DST: 1 mg Dexamethasone suppression test; UFC: urinary free cortisol, LNSC: late-night salivary cortisol; ESR: erythrocyte sedimentation rate; IL-6: interleukin-6; SHBG: steroid hormone binding globulin; HOMA: homeostatic model assessment.