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TABLE 4.

Comparison of P. aeruginosa infection course in mouse eyes challenged with wild-type PAK, nonpiliated PAKpilA::Tcr, and the twitching motility mutants PAKpilT::Tn5 and PAKpilU::Tn5

StrainInfecting dose (CFU)Ocular scoresa
Day 1Day 2Day 4Day 7
Wild-type PAK1.15 × 1073, 3, 3, 3, 33, 3, 3, 3, 33, 3, 3, 4, 43, 3, 3, 4, 4
PAKpilA::Tcr1.35 × 1070, 0, 0, 0, 00, 0, 0, 0, 00, 0, 0, 0, 00, 0, 0, 0, 1
PAKpilT::Tn51.02 × 1070, 0, 1, 1, 11, 1, 1, 1, 10, 1, 1, 1, 10, 1, 1, 1, 1
PAKpilU::Tn51.27 × 1070, 1, 1, 1, 21, 1, 1, 2, 21, 1, 1, 1, 21, 1, 1, 1, 2
aOcular grading scores are defined in the text.