| PMC full text: | Published online 2012 Jan 6. doi: 10.1093/molbev/msr320
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Table 2.
Mean Substitution Rates and the Ages of the MRCA of Main Genotypes of DENV-1 to DENV-4 Circulating in the Americas.
| Serotype | MRCA (HPD) | Year of First Report | Root State Location | Country of First Report | Rates (HPD) (subs/site/year) |
| DENV-1 | 1973 | 1977 | Grenada | Jamaica | 7.773 × 10−4 |
| (1970–1975) | (6.528 × 10−4, 9.081 × 10−4) | ||||
| DENV-2 | 1979 | 1981 | Jamaica | Cuba | 8.600 × 10−4 |
| (1978–1981) | (7.408 × 10−4, 9.836 × 10−4) | ||||
| DENV-3 | 1992 | 1994 | Nicaragua | Nicaragua and Panama | 9.851 × 10−4 |
| (1991–1993) | (7.337 × 10−4, 10.396 × 10−4) | ||||
| DENV-4 | 1979 | 1981 | Dominica | St Barthelemy, St Martin, and Dominica | 9.712 × 10−4 |
| (1978–1980) | (7.944 × 10−4, 10.627 × 10−4) |
Note.—HPD—95% highest posterior density interval.