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Table 2

Empirical Type 1 Error of Test Statistics, Based on 25,000 Replicates

Sampled GenosTrait ModelNominal LevelMASTORASTORGTAMTSCORE
AllIIA.05.049.048.049.050
AllIIIA.05.049.049.050.048
AllIVA.05.048.048.047.049
AllVA.05.051.051.052.050
RandomIIC.05.050.050.052.053
Upper tailIIA.05.049.050.050.006
Upper tailIIIA.05.049.050.049.015
Upper tailIIC.05.050.049.052.045
Even tailsIIA.05.051.051.053.108
Even tailsIIC.05.050.051.054.119
AllIIA.001.0011.0011.0010.0008
AllIIIA.001.0008.0009.0009.0008
AllIVA.001.0012.0012.0012.0010
AllVA.001.0010.0010.0010.0009
RandomIIC.001.0008.0010.0011.0009
Upper tailIIA.001.0006.0010.0012.0000
Upper tailIIIA.001.0013.0012.0011.0000
Upper tailIIC.001.0014.0015.0010.0006
Even tailsIIA.001.0008.0008.0010.0066
Even tailsIIC.001.0012.0013.0014.0089

Values in bold are those that differ significantly (p value < .01) from the nominal level by a z-test. “Sampled Genos” refers to the different genotype sampling schemes described in subsection Sampled Genotypes of the Material and Methods. The trait models are described in subsection Trait Models of the Material and Methods. For trait model II, the tested SNP has minor allele frequency .2, whereas for trait models III, IV, and V, the tested SNP has minor allele frequency .1.