| PMC full text: | Published online 2013 Jul 25. doi: 10.2215/CJN.02510213
|
Table 2.
Summary of NDRD, with and without DN, found on biopsies of patients with diabetes
| Types of NDRD (n) | NDRD Alone (n=220) | DN Plus NDRD (n=164) | P Valuea |
|---|---|---|---|
| Acute tubular necrosis (109) | 38 (17.3) | 71 (43.3) | <0.001 |
| FSGS (69) | 48 (21.8) | 21 (12.8) | 0.02 |
 Primary FSGS (6) | 6 (2.7) | 0 (0.0) | 0.03 |
| Secondary FSGS (63)b | |||
| HTN related | 19 (8.6) | 10 (6.1) | 0.35 |
| HTN plus obesity related | 16 (7.3) | 10 (6.1) | 0.65 |
| Obesity related | 4 (1.8) | 1 (0.6) | 0.30 |
| Otherc | 3 (1.4) | 0 (0.0) | 0.13 |
| Hypertensive nephrosclerosis (70)b | 39 (17.7) | 31 (18.9) | 0.77 |
| IgA nephropathy (35) | 23 (10.5) | 12 (7.3) | 0.29 |
| Membranous GN (23) | 18 (8.2) | 5 (3.0) | 0.04 |
| Pauci-immune crescentic GN (19) | 15 (6.8) | 4 (2.4) | 0.05 |
| Acute interstitial nephritis (18) | 11 (5.0) | 7 (4.3) | 0.73 |
| Amyloidosis (10) | 10 (4.5) | 0 (0) | 0.01 |
| Myeloma cast nephropathy (10) | 8 (3.6) | 2 (1.2) | 0.14 |
| Acute postinfectious GN (6) | 3 (1.4) | 3 (1.8) | 0.72 |
| Atheroembolic disease (5) | 2 (0.9) | 3 (1.8) | 0.43 |
| Others (10) | 5 (2.3) | 5 (3.0) | 0.64 |
Values are expressed as n (%). NDRD, nondiabetic renal disease; DN, diabetic nephropathy; HTN, hypertension.
aP value is from a two-sample test of proportions
bThirteen cases of secondary FSGS in the NDRD alone subgroup and 16 cases of secondary FSGS in the DN plus NDRD subgroup also showed features of hypertensive nephrosclerosis.
cIncludes increased muscle mass (n=1), solitary kidney (n=1), and familial FSGS (n=1)