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PMC full text:
Cell. Author manuscript; available in PMC 2018 Jan 26.
Published in final edited form as:
Cell. 2017 Jan 26; 168(3): 442–459.e20.
Published online 2017 Jan 19. doi: 10.1016/j.cell.2016.12.016

Figure 1

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Reprogramming factor and epigenome maps in four reprogramming stages

A) Summary of reprogramming stages and data sets produced.

B) Snapshot of indicated genomics data at a candidate genomic locus. N/A = no data. The color code represents the stage-specific chromatin states defined in (C). Red boxes mark the somatic gene Tgfb3 and the pluripotency gene Esrrb.

C) Rows represent chromatin states and their representative mnemonics, color-coded and grouped based on their putative annotation. Cells show the frequency of each histone marks, H3.3, and input for each state (ChromHMM emission probabilities).

D) Columns give % genome occupancy, median length in kilo bases (kb), and fold-enrichment of indicated features (transcription end sites, TES; transcription start sites, TSS; conservation phastCons elements; endogenous retrovirus K elements, ERVK) for each chromatin state described in (C) for MEFs and ESCs. Color-code per column from highest to lowest value.

See also Fig S1.

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