Prevalence and prognostic ability of the GOLD 2017 classification compared to the GOLD 2011 classification in a Norwegian COPD cohort

doi:10.2147/COPD.S194019

PMC full text:

Int J Chron Obstruct Pulmon Dis. 2019; 14: 1639–1655.

Published online 2019 Jul 23. doi: 10.2147/COPD.S194019

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Table S2

Characteristics of male participants in the GenKOLS study 2003–2005, by GOLD 2017 classification

	A n=148	B n=291	C n=12	D n=106	p*
mMRC dyspnea score, mean (SD)	1 (0)	2.8 (1.0)	1 (0)	3.3 (1.0)	<0.001
Exacerbations last year, mean (SD)	0.1 (0.3)	0.1 (0.3)	1.6 (0.8)	1.9 (1.3)	<0.001
% pred.post-bd FEV1, mean (SD)	62 (14)	50 (17)	51 (18)	40 (16)	<0.001
Age (yrs), mean (SD)	62 (9.5)	67 (10.2)	58 (10.9)	68 (9.6)	<0.001
Current smokers (%)	54	43	92	29	<0.001
Pack years, mean (SD)	34 (17)	35 (19)	31 (10)	39 (23)	0.47
BMI (kg/m²), mean (SD)	26 (4)	26 (4)	25 (6)	25 (5)	0.22
Diabetes (%)	5	7	0	11	0.30
Heart attack/angina (%)	16	22	8	35	0.003
High blood pressure (%)	32	31	8	30	0.39
Chronic cough (%)	55	73	38	80	0.004
Phlegm (%)	50	69	83	76	<0.001
Wheeze (%)	61	80	75	82	0.001
All-cause hosptalizations per year	2.1 (3)	4.2 (4)	3.8 (6)	7.1 (6)	<0.001
Respiratory hospitalizations days per year	0.1 (1)	0.7 (2)	1.3 (5)	1,9 (4)	<0.001
All-cause mortality (%)	18	35	17	53	<0.001
Respiratory mortality (%)	2	13	0	20	<0.001
Cardiovascular mortality (%)	1	5	8	6	0.21

Notes: N=557. *Overall test for equality of populations: Chi-square test for categorical variables with >5 observations in each cell, Fisher’s exact test for categorical variables with <5 observations in a cell (diabetes, heart attack, all-cause, respiratory and cardiovascular mortality), and Kruskal–Wallis test for continuous variables.

Abbreviations: mMRC, modified Medical Research Council dyspnea score; post-bd FEV1, post-bronchodilator forced expiratory volume in 1 s; BMI, body mass index.