Serum Proteomic Fingerprints of Adult Patients with Severe Acute Respiratory Syndrome

doi:10.1373/clinchem.2005.061689

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Clin Chem. 2006 Mar; 52(3): 421–429.

Published online 2006 Mar 1. doi: 10.1373/clinchem.2005.061689

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Table 1.

Summary of the proteomic features differentially expressed between the SARS and non-SARS control groups.

Mean (minimum–maximum) m/z	Area under ROC curve¹ (95% confidence interval)	Mean (SD) intensity of proteomic feature relative to total sum of proteomic features, %
Mean (minimum–maximum) m/z	Area under ROC curve¹ (95% confidence interval)			Non-SARS control	SARS cases
4154 (4149–4159)	0.867 (0.781–0.953)	0.145 (0.102)	0.534 (0.586)
4303 (4300–4309)	0.914 (0.842–0.985)	0.110 (0.115)	0.397 (0.204)
4469 (4466–4475)	0.898 (0.828–0.968)	0.230 (0.130)	0.664 (0.359)
4482 (4476–4489)	0.819 (0.723–0.915)	0.102 (0.079)	0.245 (0.184)
4680 (4676–4683)	0.802 (0.702–0.903)²	0.153 (0.075)	0.087 (0.034)
5908 (5903–5915)	0.995 (0.985–0.996)²	1.895 (0.716)	0.255 (0.244)
6634 (6626–6643)	0.745 (0.636–0.854)²	0.276 (0.144)	0.167 (0.091)
7769 (7761–7776)	0.733 (0.621–0.846)²	0.058 (0.054)	0.027 (0.019)
8606 (8600–8612)	0.923 (0.859–0.988)	0.239 (0.298)	1.054 (0.570)
8619 (8613–8623)	0.923 (0.861–0.985)	0.148 (0.178)	0.670 (0.424)
8635 (8630–8641)	0.915 (0.851–0.979)	0.074 (0.072)	0.331 (0.227)
8814 (8808–8820)	0.850 (0.764–0.935)	0.013 (0.020)	0.060 (0.051)
8831 (8827–8836)	0.835 (0.741–0.929)	0.015 (0.017)	0.049 (0.036)
8865 (8856–8874)	0.762 (0.656–0.868)	0.100 (0.071)	0.170 (0.076)
8937 (8930–8946)	0.901 (0.833–0.970)	0.604 (0.335)	1.612 (0.755)
8956 (8946–8968)	0.925 (0.868–0.982)	0.277 (0.168)	0.869 (0.455)
17 878 (17 860–17 902)	0.846 (0.759–0.934)	0.005 (0.004)	0.014 (0.009)
24 505 (24 465–24 553)	0.733 (0.621–0.845)	1.598 (0.828)	2.302 (0.988)
28 119 (28 064–28 171)	0.987 (0.966–1.007)	0.787 (0.496)	3.904 (1.370)
88 637 (88 474–88 736)	0.851 (0.766–0.936)^b	1.300 (0.316)	0.920 (0.207)

¹ P <0.0005 for all.

²Area under the ROC curve was calculated for 1/peak intensity.