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Search life-sciences literature (45,100,050 articles, preprints and more)

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Piperine enhances doxorubicin sensitivity in triple-negative breast cancer by targeting the PI3K/Akt/mTOR pathway and cancer stem cells.
Hakeem AN, El-Kersh DM, Hammam O, Elhosseiny A, Zaki A, Kamel K, Yasser L, Barsom M, Ahmed M, Gamal M, Attia YM
Sci Rep, 14(1):18181, 06 Aug 2024
Cited by: 0 articles | PMID: 39107323 | PMCID: PMC11303729
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2-methoxyestradiol sensitizes tamoxifen-resistant MCF-7 breast cancer cells via downregulating HIF-1α.
Attia YM, Mokhlis HA, Ismail A, Doghish AS, Sobhy MH, Hassanein SS, El-Dakroury WA, Mariee AD, Salama SA, Sharaky M
Med Oncol, 41(9):232, 21 Aug 2024
Cited by: 1 article | PMID: 39167288 | PMCID: PMC11339102
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Novel 3,6-Disubstituted Pyridazine Derivatives Targeting JNK1 Pathway: Scaffold Hopping and Hybridization-Based Design, Synthesis, Molecular Modeling, and In Vitro and In Vivo Anticancer Evaluation.
Shaalan MM, Osman EEA, Attia YM, Hammam OA, George RF, Naguib BH
ACS Omega, 9(35):37310-37329, 19 Aug 2024
Cited by: 0 articles | PMID: 39246493 | PMCID: PMC11375727
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Novel fast dissolving freeze dried sublingual baicalin tablets for enhanced hepatoprotective effect: in-vitro characterization, cell viability, and in-vivo evaluation.
Abdelrazek FN, Shalaby RA, Fahim SA, Essam RM, Anis SE, Attia YM, Abd El Malak NS
Pharm Dev Technol, 29(4):371-382, 13 Apr 2024
Cited by: 0 articles | PMID: 38613468
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The role of vitamin D3 in modulating the interplay between NLRP3 inflammasome and autophagy in NASH.
Abdelrahman BA, Hammam OA, El-Khatib AS, Attia YM
Biochem Biophys Res Commun, 688:149122, 24 Oct 2023
Cited by: 2 articles | PMID: 37951152
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Insights into the role of vitamin D in targeting the culprits of non-alcoholic fatty liver disease.
Abdelrahman BA, El-Khatib AS, Attia YM
Life Sci, 332:122124, 22 Sep 2023
Cited by: 2 articles | PMID: 37742738
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Thymoquinone Suppresses Angiogenesis in DEN-Induced Hepatocellular Carcinoma by Targeting miR-1-3p.
Tadros SA, Attia YM, Maurice NW, Fahim SA, Abdelwahed FM, Ibrahim S, Badary OA
Int J Mol Sci, 23(24):15904, 14 Dec 2022
Cited by: 7 articles | PMID: 36555545 | PMCID: PMC9781440
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Elafibranor modulates ileal macrophage polarization to restore intestinal integrity in NASH: Potential crosstalk between ileal IL-10/STAT3 and hepatic TLR4/NF-κB axes.
Hakeem AN, Kamal MM, Tawfiq RA, Abdelrahman BA, Hammam OA, Elmazar MM, El-Khatib AS, Attia YM
Biomed Pharmacother, 157:114050, 30 Nov 2022
Cited by: 6 articles | PMID: 36462310
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Hydroxycitric acid reverses tamoxifen resistance through inhibition of ATP citrate lyase.
Ismail A, Mokhlis HA, Sharaky M, Sobhy MH, Hassanein SS, Doghish AS, Salama SA, Mariee AD, Attia YM
Pathol Res Pract, 240:154211, 11 Nov 2022
Cited by: 5 articles | PMID: 36401980
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Molecular Design, Spectroscopic, DFT, Pharmacological, and Molecular Docking Studies of Novel Ruthenium(III)-Schiff Base Complex: An Inhibitor of Progression in HepG2 Cells.
Noureldeen AFH, Aziz SW, Shouman SA, Mohamed MM, Attia YM, Ramadan RM, Elhady MM
Int J Environ Res Public Health, 19(20):13624, 20 Oct 2022
Cited by: 4 articles | PMID: 36294202 | PMCID: PMC9603487
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Investigating the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer.
Badawi NM, Attia YM, El-Kersh DM, Hammam OA, Khalifa MKA
Int J Nanomedicine, 17:733-750, 18 Feb 2022
Cited by: 6 articles | PMID: 35210772 | PMCID: PMC8863342
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In Vitro Cytotoxic Activity and Phytochemical Characterization (UPLC/T-TOF-MS/MS) of the Watermelon (Citrullus lanatus) Rind Extract.
El Gizawy HA, El-Haddad AE, Attia YM, Fahim SA, Zafer MM, Saadeldeen AM
Molecules, 27(8):2480, 12 Apr 2022
Cited by: 2 articles | PMID: 35458677 | PMCID: PMC9024807
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Obeticholic acid orchestrates the crosstalk between ileal autophagy and tight junctions in non-alcoholic steatohepatitis: Role of TLR4/TGF-β1 axis.
Tawfiq RA, Nassar NN, Hammam OA, Allam RM, Elmazar MM, Abdallah DM, Attia YM
Chem Biol Interact, 361:109953, 16 Apr 2022
Cited by: 7 articles | PMID: 35439472
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Targeting CDK7 reverses tamoxifen resistance through regulating stemness in ER+ breast cancer.
Attia YM, Salama SA, Shouman SA, Ivan C, Elsayed AM, Amero P, Rodriguez-Aguayo C, Lopez-Berestein G
Pharmacol Rep, 74(2):366-378, 09 Jan 2022
Cited by: 2 articles | PMID: 35000145
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Conversion of RNA Aptamer into Modified DNA Aptamers Provides for Prolonged Stability and Enhanced Antitumor Activity.
Amero P, Lokesh GLR, Chaudhari RR, Cardenas-Zuniga R, Schubert T, Attia YM, Montalvo-Gonzalez E, Elsayed AM, Ivan C, Wang Z, Cristini V, Franciscis V, Zhang S, Volk DE, Mitra R, Rodriguez-Aguayo C, Sood AK, Lopez-Berestein G
J Am Chem Soc, 143(20):7655-7670, 14 May 2021
Cited by: 14 articles | PMID: 33988982
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Anti-estrogenic and anti-aromatase activities of citrus peels major compounds in breast cancer.
El-Kersh DM, Ezzat SM, Salama MM, Mahrous EA, Attia YM, Ahmed MS, Elmazar MM
Sci Rep, 11(1):7121, 29 Mar 2021
Cited by: 14 articles | PMID: 33782546 | PMCID: PMC8007834
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Histopathological evaluation of insulin-DMSO formula designed for direct nose-to-brain delivery.
Maher MA, Kandeel WA, Hammam OA, Attia YM, Mahmoud S, Salah M
Histol Histopathol, 37(5):431-439, 18 Jan 2021
Cited by: 4 articles | PMID: 35040114
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Activation of FXR modulates SOCS3/Jak2/STAT3 signaling axis in a NASH-dependent hepatocellular carcinoma animal model.
Attia YM, Tawfiq RA, Gibriel AA, Ali AA, Kassem DH, Hammam OA, Elmazar MM
Biochem Pharmacol, 186:114497, 04 Mar 2021
Cited by: 17 articles | PMID: 33675775
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Blockade of CDK7 Reverses Endocrine Therapy Resistance in Breast Cancer.
Attia YM, Shouman SA, Salama SA, Ivan C, Elsayed AM, Amero P, Rodriguez-Aguayo C, Lopez-Berestein G
Int J Mol Sci, 21(8):E2974, 23 Apr 2020
Cited by: 13 articles | PMID: 32340192 | PMCID: PMC7215326
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Crosstalk between aldehyde dehydrogenase-1 and chemoresistance in breast cancer: Insights into the role of vitamin D3.
Attia YM, Hammam OA, Ammar RA, Mansour MT, Elmazar MM
Life Sci, 253:117733, 28 Apr 2020
Cited by: 5 articles | PMID: 32360127
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Author Correction: Verbascoside: Identification, Quantification, and Potential Sensitization of Colorectal Cancer Cells to 5-FU by Targeting PI3K/AKT Pathway.
Attia YM, El-Kersh DM, Wagdy HA, Elmazar MM
Sci Rep, 9(1):18659, 04 Dec 2019
Cited by: 0 articles | PMID: 31796874 | PMCID: PMC6890643
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Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma.
Mohamady S, Ismail MI, Mogheith SM, Attia YM, Taylor SD
Bioorg Chem, 94:103433, 19 Nov 2019
Cited by: 6 articles | PMID: 31785857
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Inhibition of aldehyde dehydrogenase-1 and p-glycoprotein-mediated multidrug resistance by curcumin and vitamin D3 increases sensitivity to paclitaxel in breast cancer.
Attia YM, El-Kersh DM, Ammar RA, Adel A, Khalil A, Walid H, Eskander K, Hamdy M, Reda N, Mohsen NE, Al-Toukhy GM, Mansour MT, Elmazar MM
Chem Biol Interact, 315:108865, 16 Oct 2019
Cited by: 27 articles | PMID: 31628941
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Structure-based drug design, synthesis, In vitro, and In vivo biological evaluation of indole-based biomimetic analogs targeting estrogen receptor-α inhibition.
Hendy MS, Ali AA, Ahmed L, Hossam R, Mostafa A, Elmazar MM, Naguib BH, Attia YM, Ahmed MS
Eur J Med Chem, 166:281-290, 30 Jan 2019
Cited by: 7 articles | PMID: 30731397
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Structural re-positioning, in silico molecular modelling, oxidative degradation, and biological screening of linagliptin as adenosine 3 receptor (ADORA3) modulators targeting hepatocellular carcinoma.
Ayoub BM, Attia YM, Ahmed MS
J Enzyme Inhib Med Chem, 33(1):858-866, 01 Dec 2018
Cited by: 6 articles | PMID: 29768061 | PMCID: PMC6010121
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1-25 of 38 results

1 2

Search life-sciences literature (45,100,050 articles, preprints and more)

Search results

Piperine enhances doxorubicin sensitivity in triple-negative breast cancer by targeting the PI3K/Akt/mTOR pathway and cancer stem cells.

2-methoxyestradiol sensitizes tamoxifen-resistant MCF-7 breast cancer cells via downregulating HIF-1α.

Novel 3,6-Disubstituted Pyridazine Derivatives Targeting JNK1 Pathway: Scaffold Hopping and Hybridization-Based Design, Synthesis, Molecular Modeling, and In Vitro and In Vivo Anticancer Evaluation.

Novel fast dissolving freeze dried sublingual baicalin tablets for enhanced hepatoprotective effect: in-vitro characterization, cell viability, and in-vivo evaluation.

The role of vitamin D3 in modulating the interplay between NLRP3 inflammasome and autophagy in NASH.

Insights into the role of vitamin D in targeting the culprits of non-alcoholic fatty liver disease.

Thymoquinone Suppresses Angiogenesis in DEN-Induced Hepatocellular Carcinoma by Targeting miR-1-3p.

Elafibranor modulates ileal macrophage polarization to restore intestinal integrity in NASH: Potential crosstalk between ileal IL-10/STAT3 and hepatic TLR4/NF-κB axes.

Hydroxycitric acid reverses tamoxifen resistance through inhibition of ATP citrate lyase.

Molecular Design, Spectroscopic, DFT, Pharmacological, and Molecular Docking Studies of Novel Ruthenium(III)-Schiff Base Complex: An Inhibitor of Progression in HepG2 Cells.

Investigating the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer.

In Vitro Cytotoxic Activity and Phytochemical Characterization (UPLC/T-TOF-MS/MS) of the Watermelon (Citrullus lanatus) Rind Extract.

Obeticholic acid orchestrates the crosstalk between ileal autophagy and tight junctions in non-alcoholic steatohepatitis: Role of TLR4/TGF-β1 axis.

Targeting CDK7 reverses tamoxifen resistance through regulating stemness in ER+ breast cancer.

Conversion of RNA Aptamer into Modified DNA Aptamers Provides for Prolonged Stability and Enhanced Antitumor Activity.

Anti-estrogenic and anti-aromatase activities of citrus peels major compounds in breast cancer.

Histopathological evaluation of insulin-DMSO formula designed for direct nose-to-brain delivery.

Activation of FXR modulates SOCS3/Jak2/STAT3 signaling axis in a NASH-dependent hepatocellular carcinoma animal model.

Blockade of CDK7 Reverses Endocrine Therapy Resistance in Breast Cancer.

Crosstalk between aldehyde dehydrogenase-1 and chemoresistance in breast cancer: Insights into the role of vitamin D3.

Author Correction: Verbascoside: Identification, Quantification, and Potential Sensitization of Colorectal Cancer Cells to 5-FU by Targeting PI3K/AKT Pathway.

Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma.

Inhibition of aldehyde dehydrogenase-1 and p-glycoprotein-mediated multidrug resistance by curcumin and vitamin D3 increases sensitivity to paclitaxel in breast cancer.

Structure-based drug design, synthesis, In vitro, and In vivo biological evaluation of indole-based biomimetic analogs targeting estrogen receptor-α inhibition.

Structural re-positioning, in silico molecular modelling, oxidative degradation, and biological screening of linagliptin as adenosine 3 receptor (ADORA3) modulators targeting hepatocellular carcinoma.

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