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Characterizing Enoxaparin's Population Pharmacokinetics to Guide Dose Individualization in the Pediatric Population.
Carreño FO, Gerhart JG, Helfer VE, Sinha J, Kumar KR, Kirkpatrick C, Hornik CP, Gonzalez D, Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee
Clin Pharmacokinet, 63(7):999-1014, 02 Jul 2024
Cited by: 0 articles | PMID: 38955947
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Leveraging physiologically based pharmacokinetic modeling to optimize dosing for lopinavir/ritonavir with rifampin in pediatric patients.
Salerno SN, Capparelli EV, McIlleron H, Gerhart JG, Dumond JB, Kashuba ADM, Denti P, Gonzalez D
Pharmacotherapy, 43(7):638-649, 08 Jun 2022
Cited by: 1 article | PMID: 35607886 | PMCID: PMC9684348
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Physiologically Based Pharmacokinetic Modeling of Metformin in Children and Adolescents With Obesity.
Ford JL, Gerhart JG, Edginton AN, Yanovski JA, Hon YY, Gonzalez D
J Clin Pharmacol, 62(8):960-969, 02 Mar 2022
Cited by: 10 articles | PMID: 35119103 | PMCID: PMC9288496
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Use of Real-World Data and Physiologically-Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity.
Gerhart JG, Carreño FO, Loop MS, Lee CR, Edginton AN, Sinha J, Kumar KR, Kirkpatrick CM, Hornik CP, Gonzalez D, Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee
Clin Pharmacol Ther, 112(2):391-403, 18 May 2022
Cited by: 7 articles | PMID: 35451072 | PMCID: PMC9504927
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Use of physiologically-based pharmacokinetic modeling to inform dosing of the opioid analgesics fentanyl and methadone in children with obesity.
Gerhart JG, Carreño FO, Ford JL, Edginton AN, Perrin EM, Watt KM, Muller WJ, Atz AM, Al-Uzri A, Delmore P, Gonzalez D, Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee
CPT Pharmacometrics Syst Pharmacol, 11(6):778-791, 02 May 2022
Cited by: 3 articles | PMID: 35491971 | PMCID: PMC9197535
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Characterizing Pharmacokinetics in Children With Obesity-Physiological, Drug, Patient, and Methodological Considerations.
Gerhart JG, Balevic S, Sinha J, Perrin EM, Wang J, Edginton AN, Gonzalez D
Front Pharmacol, 13:818726, 10 Mar 2022
Cited by: 16 articles | PMID: 35359853 | PMCID: PMC8960278
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Genomic Surveillance for SARS-CoV-2 Variants: Predominance of the Delta (B.1.617.2) and Omicron (B.1.1.529) Variants - United States, June 2021-January 2022.
Lambrou AS, Shirk P, Steele MK, Paul P, Paden CR, Cadwell B, Reese HE, Aoki Y, Hassell N, Zheng XY, Talarico S, Chen JC, Oberste MS, Batra D, McMullan LK, Halpin AL, Galloway SE, MacCannell DR, Kondor R, [...] Strain Surveillance and Emerging Variants NS3 Working Group
MMWR Morb Mortal Wkly Rep, 71(6):206-211, 11 Feb 2022
Cited by: 113 articles | PMID: 35143464 | PMCID: PMC8830620
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Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling.
Gerhart JG, Carreño FO, Edginton AN, Sinha J, Perrin EM, Kumar KR, Rikhi A, Hornik CP, Harris V, Ganguly S, Cohen-Wolkowiez M, Gonzalez D, Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee
Clin Pharmacokinet, 61(2):307-320, 07 Oct 2021
Cited by: 16 articles | PMID: 34617262 | PMCID: PMC8813791
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Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants.
Ganguly S, Edginton AN, Gerhart JG, Cohen-Wolkowiez M, Greenberg RG, Gonzalez D, Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee
Clin Pharmacokinet, 60(12):1591-1604, 22 Jun 2021
Cited by: 13 articles | PMID: 34155614 | PMCID: PMC8616812
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External Evaluation of Two Pediatric Population Pharmacokinetics Models of Oral Trimethoprim and Sulfamethoxazole.
Wu YSS, Cohen-Wolkowiez M, Hornik CP, Gerhart JG, Autmizguine J, Cobbaert M, Gonzalez D, Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee
Antimicrob Agents Chemother, 65(7):e0214920, 17 Jun 2021
Cited by: 4 articles | PMID: 33903114 | PMCID: PMC8407045
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Physiologically-Based Pharmacokinetic Modeling Characterizes the CYP3A-Mediated Drug-Drug Interaction Between Fluconazole and Sildenafil in Infants.
Salerno SN, Edginton A, Gerhart JG, Laughon MM, Ambalavanan N, Sokol GM, Hornik CD, Stewart D, Mills M, Martz K, Gonzalez D, Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee
Clin Pharmacol Ther, 109(1):253-262, 22 Aug 2020
Cited by: 15 articles | PMID: 32691891 | PMCID: PMC8138939
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Population Pharmacokinetics of Metoclopramide in Infants, Children, and Adolescents.
Ge S, Mendley SR, Gerhart JG, Melloni C, Hornik CP, Sullivan JE, Atz A, Delmore P, Tremoulet A, Harper B, Payne E, Lin S, Erinjeri J, Cohen-Wolkowiez M, Gonzalez D, Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee
Clin Transl Sci, 13(6):1189-1198, 27 May 2020
Cited by: 5 articles | PMID: 32324313 | PMCID: PMC7719387
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The Population Pharmacokinetics of High-Dose Methotrexate in Infants with Acute Lymphoblastic Leukemia Highlight the Need for Bedside Individualized Dose Adjustment: A Report from the Children's Oncology Group.
Beechinor RJ, Thompson PA, Hwang MF, Vargo RC, Bomgaars LR, Gerhart JG, Dreyer ZE, Gonzalez D
Clin Pharmacokinet, 58(7):899-910, 01 Jul 2019
Cited by: 15 articles | PMID: 30810947 | PMCID: PMC6658326
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Physiologically-Based Pharmacokinetic Modeling of Fluconazole Using Plasma and Cerebrospinal Fluid Samples From Preterm and Term Infants.
Gerhart JG, Watt KM, Edginton A, Wade KC, Salerno SN, Benjamin DK, Smith PB, Hornik CP, Cohen-Wolkowiez M, Duara S, Ross A, Shattuck K, Stewart DL, Neu N, Gonzalez D, Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee
CPT Pharmacometrics Syst Pharmacol, 8(7):500-510, 22 May 2019
Cited by: 7 articles | PMID: 31087536 | PMCID: PMC6656941
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Multiple Acquisitions of Pathogen-Derived Francisella Endosymbionts in Soft Ticks.
Gerhart JG, Auguste Dutcher H, Brenner AE, Moses AS, Grubhoffer L, Raghavan R
Genome Biol Evol, 10(2):607-615, 01 Feb 2018
Cited by: 24 articles | PMID: 29385445 | PMCID: PMC5804916
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A Francisella-like endosymbiont in the Gulf Coast tick evolved from a mammalian pathogen.
Gerhart JG, Moses AS, Raghavan R
Sci Rep, 6:33670, 20 Sep 2016
Cited by: 45 articles | PMID: 27645766 | PMCID: PMC5028885
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