AUTH:"Hural J" - Search results

Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial.

Fong Y, Dang L, Zhang B, Fintzi J, Chen S, Wang J, Rouphael NG, Branche AR, Diemert DJ, Falsey AR, Losada C, Baden LR, Frey SE, Whitaker JA, Little SJ, Kamidani S, Walter EB, Novak RM, Rupp R, [...] Coronavirus Variant Immunologic Landscape Trial (COVAIL) Study Team

Clin Infect Dis, ciae465, 26 Sep 2024

Cited by: 0 articles | PMID: 39325506

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Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study.

Kenny A, van Duijn J, Dintwe O, Heptinstall J, Burnham R, Sawant S, Zhang L, Mielke D, Khuzwayo S, Omar FL, Stanfield-Oakley S, Keyes T, Dunn B, Goodman D, Fong Y, Benkeser D, Zou R, Hural J, Hyrien O, [...] Imbokodo Study and Correlates Group

EBioMedicine, 108:105320, 04 Sep 2024

Cited by: 0 articles | PMID: 39236556 | PMCID: PMC11404224

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Mosaic HIV-1 vaccine regimen in southern African women (Imbokodo/HVTN 705/HPX2008): a randomised, double-blind, placebo-controlled, phase 2b trial.

Gray GE, Mngadi K, Lavreys L, Nijs S, Gilbert PB, Hural J, Hyrien O, Juraska M, Luedtke A, Mann P, McElrath MJ, Odhiambo JA, Stieh DJ, van Duijn J, Takalani AN, Willems W, Tapley A, Tomaras GD, Van Hoof J, [...] Imbokodo/HVTN 705/HPX2008 Study Group

Lancet Infect Dis, 24(11):1201-1212, 19 Jul 2024

Cited by: 2 articles | PMID: 39038477

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HIV Diagnostics and Vaccines: It Takes Two to Tango.

Colón W, Oriol-Mathieu V, Hural J, Hattingh L, Adungo F, Lagatie O, Lavreys L, Allen M, Anzala O, Espy N, Fransen K, Garcia PJ, Maciel M, Murtagh M, Peel SA, Peeling RW, Tan LLJ, Warren M, Pau MG, D'Souza PM

J Infect Dis, 229(6):1919-1925, 01 Jun 2024

Cited by: 1 article | PMID: 38451247

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Prevention efficacy of the broadly neutralizing antibody VRC01 depends on HIV-1 envelope sequence features.

Juraska M, Bai H, deCamp AC, Magaret CA, Li L, Gillespie K, Carpp LN, Giorgi EE, Ludwig J, Molitor C, Hudson A, Williamson BD, Espy N, Simpkins B, Rudnicki E, Shao D, Rossenkhan R, Edlefsen PT, Westfall DH, [...] Mullins JI

Proc Natl Acad Sci U S A, 121(4):e2308942121, 19 Jan 2024

Cited by: 4 articles | PMID: 38241441 | PMCID: PMC10823214

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Polytopic fractional delivery of an HIV vaccine alters cellular responses and results in increased epitope breadth in a phase 1 randomized trial.

Miner MD, deCamp A, Grunenberg N, De Rosa SC, Fiore-Gartland A, Bar K, Spearman P, Allen M, Yu PC, Manso B, Frahm N, Kalams S, Baden L, Keefer MC, Scott HM, Novak R, Van Tieu H, Tomaras GD, Kublin JG, [...] HVTN 085 Study Team

EBioMedicine, 100:104987, 01 Feb 2024

Cited by: 1 article | PMID: 38306894 | PMCID: PMC10847480

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Adults on pre-exposure prophylaxis (tenofovir-emtricitabine) have faster clearance of anti-HIV monoclonal antibody VRC01.

Huang Y, Zhang L, Karuna S, Andrew P, Juraska M, Weiner JA, Angier H, Morgan E, Azzam Y, Swann E, Edupuganti S, Mgodi NM, Ackerman ME, Donnell D, Gama L, Anderson PL, Koup RA, Hural J, Cohen MS, [...] Lemos MP

Nat Commun, 14(1):7813, 28 Nov 2023

Cited by: 2 articles | PMID: 38016958 | PMCID: PMC10684488

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Efficacy of a monovalent (D614) SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in adults: a phase 3, multi-country study.

Dayan GH, Rouphael N, Walsh SR, Chen A, Grunenberg N, Allen M, Antony J, Bhate AS, Beresnev T, Bonaparte MI, Celle M, Ceregido MA, Corey L, Fu B, Grillet MH, Keshtkar-Jahromi M, Juraska M, Kee JJ, Kaali S, [...] VAT00008 study team

EClinicalMedicine, 64:102168, 12 Sep 2023

Cited by: 2 articles | PMID: 37936652 | PMCID: PMC10626161

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Cross-protocol assessment of induction and durability of VISP/R in HIV preventive vaccine trial participants.

Espy N, Han X, Grant S, Kwara E, Lakshminarayanan B, Stirewalt M, Seaton KE, Tomaras GD, Goecker E, McElrath J, Andriesen J, Huang Y, Walsh SR, Hural J

PLOS Glob Public Health, 3(6):e0002037, 08 Jun 2023

Cited by: 1 article | PMID: 37289667 | PMCID: PMC10249892

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Neutralization profiles of HIV-1 viruses from the VRC01 Antibody Mediated Prevention (AMP) trials.

Mkhize NN, Yssel AEJ, Kaldine H, van Dorsten RT, Woodward Davis AS, Beaume N, Matten D, Lambson B, Modise T, Kgagudi P, York T, Westfall DH, Giorgi EE, Korber B, Anthony C, Mapengo RE, Bekker V, Domin E, Eaton A, [...] Morris L

PLoS Pathog, 19(6):e1011469, 29 Jun 2023

Cited by: 7 articles | PMID: 37384759 | PMCID: PMC10337935

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Pharmacokinetic serum concentrations of VRC01 correlate with prevention of HIV-1 acquisition.

Seaton KE, Huang Y, Karuna S, Heptinstall JR, Brackett C, Chiong K, Zhang L, Yates NL, Sampson M, Rudnicki E, Juraska M, deCamp AC, Edlefsen PT, Mullins JI, Williamson C, Rossenkhan R, Giorgi EE, Kenny A, Angier H, [...] Tomaras GD

EBioMedicine, 93:104590, 08 Jun 2023

Cited by: 10 articles | PMID: 37300931 | PMCID: PMC10363420

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Lower SARS-CoV-2-specific humoral immunity in people living with HIV-1 recovered from nonhospitalized COVID-19.

Schuster DJ, Karuna S, Brackett C, Wesley M, Li SS, Eisel N, Tenney D, Hilliard S, Yates NL, Heptinstall JR, Williams LD, Shen X, Rolfe R, Cabello R, Zhang L, Sawant S, Hu J, Randhawa AK, Hyrien O, [...] HVTN 405/HPTN 1901 Study Team

JCI Insight, 7(21):e158402, 08 Nov 2022

Cited by: 8 articles | PMID: 36136590 | PMCID: PMC9675463

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Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition.

Gilbert PB, Huang Y, deCamp AC, Karuna S, Zhang Y, Magaret CA, Giorgi EE, Korber B, Edlefsen PT, Rossenkhan R, Juraska M, Rudnicki E, Kochar N, Huang Y, Carpp LN, Barouch DH, Mkhize NN, Hermanus T, Kgagudi P, [...] Morris L

Nat Med, 28(9):1924-1932, 22 Aug 2022

Cited by: 42 articles | PMID: 35995954 | PMCID: PMC9499869

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Achieving intracellular cytokine staining assay concordance on two continents to assess HIV vaccine-induced T-cell responses.

Dintwe OB, De Rosa SC, Huang Y, Flach BS, Manso B, Carter D, Omar FL, Schwedhelm KV, Yu C, Lu H, Morris D, Kee JJ, Voillet V, Stirewalt M, Hural J, Moodie Z, Frahm N, Cohen KW, McElrath MJ, Andersen-Nissen E

J Leukoc Biol, 112(5):1167-1181, 22 Jul 2022

Cited by: 0 articles | PMID: 35866359 | PMCID: PMC10229754

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Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant.

Lyke KE, Atmar RL, Islas CD, Posavad CM, Szydlo D, Paul Chourdhury R, Deming ME, Eaton A, Jackson LA, Branche AR, El Sahly HM, Rostad CA, Martin JM, Johnston C, Rupp RE, Mulligan MJ, Brady RC, Frenck RW, Bäcker M, [...] DMID 21-0012 Study Group

Cell Rep Med, 3(7):100679, 20 Jun 2022

Cited by: 108 articles | PMID: 35798000 | PMCID: PMC9212999

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Analysis of the HIV Vaccine Trials Network 702 Phase 2b-3 HIV-1 Vaccine Trial in South Africa Assessing RV144 Antibody and T-Cell Correlates of HIV-1 Acquisition Risk.

Moodie Z, Dintwe O, Sawant S, Grove D, Huang Y, Janes H, Heptinstall J, Omar FL, Cohen K, De Rosa SC, Zhang L, Yates NL, Sarzotti-Kelsoe M, Seaton KE, Laher F, Bekker LG, Malahleha M, Innes C, Kassim S, [...] McElrath MJ

J Infect Dis, 226(2):246-257, 01 Aug 2022

Cited by: 18 articles | PMID: 35758878 | PMCID: PMC9890908

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High Asymptomatic Carriage With the Omicron Variant in South Africa.

Garrett N, Tapley A, Andriesen J, Seocharan I, Fisher LH, Bunts L, Espy N, Wallis CL, Randhawa AK, Miner MD, Ketter N, Yacovone M, Goga A, Huang Y, Hural J, Kotze P, Bekker LG, Gray GE, Corey L, Ubuntu Study Team

Clin Infect Dis, 75(1):e289-e292, 01 Aug 2022

Cited by: 66 articles | PMID: 35353885 | PMCID: PMC9383623

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Development of flow cytometry-based assays to assess the ability of antibodies to bind to SARS-CoV-2-infected and spike-transfected cells and mediate NK cell degranulation.

Mielke D, Stanfield-Oakley S, Jha S, Keyes T, Zalaquett A, Dunn B, Rodgers N, Oguin T, Sempowski GD, Binder RA, Gray GC, Karuna S, Corey L, Hural J, Tomaras GD, Pollara J, Ferrari G

Cytometry A, 101(6):483-496, 01 Apr 2022

Cited by: 4 articles | PMID: 35301794 | PMCID: PMC9087172

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Infusion Reactions After Receiving the Broadly Neutralizing Antibody VRC01 or Placebo to Reduce HIV-1 Acquisition: Results From the Phase 2b Antibody-Mediated Prevention Randomized Trials.

Takuva S, Karuna ST, Juraska M, Rudnicki E, Edupuganti S, Anderson M, De La Grecca R, Gaudinski MR, Sehurutshi A, Orrell C, Naidoo L, Valencia J, Villela LM, Walsh SR, Andrew P, Karg C, Randhawa A, Hural J, Gomez Lorenzo MM, [...] HVTN 703/HPTN 081 and HVTN 704/HPTN 085 Study Teams

J Acquir Immune Defic Syndr, 89(4):405-413, 01 Apr 2022

Cited by: 6 articles | PMID: 34923559 | PMCID: PMC9555144

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Safety and Immunogenicity of a Third Dose of SARS-CoV-2 mRNA Vaccine — An Interim Analysis

Anderson E, Jackson L, Rouphael N, Widge A, Montefiori D, Doria-Rose N, Suthar M, Cohen K, O'Connell S, Makowski M, Makhene M, Buchanan W, Spearman P, Creech CB, O'Dell S, Schmidt S, Leav B, Bennett H, Pajon R, [...] Roberts P

Research Square, 03 May 2022

Cited by: 0 articles | PPR: PPR487706

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Reactogenicity, Safety, and Serological and Cellular Immunogenicity of a Booster Dose of SARS-CoV-2 mRNA Prototype, Variant, and Bivalent Vaccines

Anderson EJ, Jackson LA, Rouphael NG, Widge AT, Montefiori D, Doria-Rose NA, Suthar M, Cohen KW, O’Connell S, Makowski M, Makhene M, Buchanan W, Spearman P, Creech CB, O’Dell S, Schmidt SD, Leav B, Bennett H, Pajon R, [...] Roberts PC

Research Square, 26 Apr 2022

Cited by: 0 articles | PPR: PPR485846

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Homologous and Heterologous Covid-19 Booster Vaccinations.

Atmar RL, Lyke KE, Deming ME, Jackson LA, Branche AR, El Sahly HM, Rostad CA, Martin JM, Johnston C, Rupp RE, Mulligan MJ, Brady RC, Frenck RW, Bäcker M, Kottkamp AC, Babu TM, Rajakumar K, Edupuganti S, Dobrzynski D, [...] DMID 21-0012 Study Group

N Engl J Med, 386(11):1046-1057, 26 Jan 2022

Cited by: 352 articles | PMID: 35081293 | PMCID: PMC8820244

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Lower SARS-CoV-2-Specific Humoral Immunity in People Living With HIV-1 Recovered From Symptomatic Non-Hospitalized COVID-19

Schuster DJ, Karuna ST, Brackett C, Wesley M, Li SS, Eisel N, Tenney D, Hilliard S, Yates NL, Heptinstall J, Williams L, Shen X, Rolfe R, Cabello R, Zhang L, Sawant S, Hu J, Randhawa A, Hyrien O, [...] Team H41S

SSRN, 04 Jan 2022

Cited by: 0 articles | PPR: PPR601941

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Calibration of two validated SARS-CoV-2 pseudovirus neutralization assays for COVID-19 vaccine evaluation.

Huang Y, Borisov O, Kee JJ, Carpp LN, Wrin T, Cai S, Sarzotti-Kelsoe M, McDanal C, Eaton A, Pajon R, Hural J, Posavad CM, Gill K, Karuna S, Corey L, McElrath MJ, Gilbert PB, Petropoulos CJ, Montefiori DC

Sci Rep, 11(1):23921, 14 Dec 2021

Cited by: 38 articles | PMID: 34907214 | PMCID: PMC8671391

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Calibration of Two Validated SARS-CoV-2 Pseudovirus Neutralization Assays for COVID-19 Vaccine Evaluation

Huang Y, Borisov O, Kee JJ, Carpp L, Wrin T, Cai S, Sarzotti-Kelsoe M, McDanal C, Eaton A, Pajon R, Hural J, Posavad C, Gill K, Karuna S, Corey L, McElrath MJ, Gilbert P, Petropoulos C, Montefiori D

Research Square, 02 Sep 2021

Cited by: 0 articles | PPR: PPR390263

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Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial.

Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study.

Mosaic HIV-1 vaccine regimen in southern African women (Imbokodo/HVTN 705/HPX2008): a randomised, double-blind, placebo-controlled, phase 2b trial.

HIV Diagnostics and Vaccines: It Takes Two to Tango.

Prevention efficacy of the broadly neutralizing antibody VRC01 depends on HIV-1 envelope sequence features.

Polytopic fractional delivery of an HIV vaccine alters cellular responses and results in increased epitope breadth in a phase 1 randomized trial.

Adults on pre-exposure prophylaxis (tenofovir-emtricitabine) have faster clearance of anti-HIV monoclonal antibody VRC01.

Efficacy of a monovalent (D614) SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant in adults: a phase 3, multi-country study.

Cross-protocol assessment of induction and durability of VISP/R in HIV preventive vaccine trial participants.

Neutralization profiles of HIV-1 viruses from the VRC01 Antibody Mediated Prevention (AMP) trials.

Pharmacokinetic serum concentrations of VRC01 correlate with prevention of HIV-1 acquisition.

Lower SARS-CoV-2-specific humoral immunity in people living with HIV-1 recovered from nonhospitalized COVID-19.

Neutralization titer biomarker for antibody-mediated prevention of HIV-1 acquisition.

Achieving intracellular cytokine staining assay concordance on two continents to assess HIV vaccine-induced T-cell responses.

Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant.

Analysis of the HIV Vaccine Trials Network 702 Phase 2b-3 HIV-1 Vaccine Trial in South Africa Assessing RV144 Antibody and T-Cell Correlates of HIV-1 Acquisition Risk.

High Asymptomatic Carriage With the Omicron Variant in South Africa.

Development of flow cytometry-based assays to assess the ability of antibodies to bind to SARS-CoV-2-infected and spike-transfected cells and mediate NK cell degranulation.

Infusion Reactions After Receiving the Broadly Neutralizing Antibody VRC01 or Placebo to Reduce HIV-1 Acquisition: Results From the Phase 2b Antibody-Mediated Prevention Randomized Trials.

Safety and Immunogenicity of a Third Dose of SARS-CoV-2 mRNA Vaccine — An Interim Analysis

Reactogenicity, Safety, and Serological and Cellular Immunogenicity of a Booster Dose of SARS-CoV-2 mRNA Prototype, Variant, and Bivalent Vaccines

Homologous and Heterologous Covid-19 Booster Vaccinations.

Lower SARS-CoV-2-Specific Humoral Immunity in People Living With HIV-1 Recovered From Symptomatic Non-Hospitalized COVID-19

Calibration of two validated SARS-CoV-2 pseudovirus neutralization assays for COVID-19 vaccine evaluation.

Calibration of Two Validated SARS-CoV-2 Pseudovirus Neutralization Assays for COVID-19 Vaccine Evaluation

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