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Search life-sciences literature (45,104,145 articles, preprints and more)

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Inflammation-induced loss of CFTR-expressing airway ionocytes in non-eosinophilic asthma.
Chen L, A Hoefel G, Pathinayake PS, Reid A, Pillar AL, Kelly C, Tan H, Ali A, Kim RY, Hansbro PM, Brody SL, Foster PS, Horvat JC, Riveros C, Awatade N, Wark PAB, Kaiko GE
Respirology, 02 Oct 2024
Cited by: 0 articles | PMID: 39358991
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The hypoxia-inducible factor EPAS1 is required for spermatogonial stem cell function in regenerative conditions.
Bernstein IR, Nixon B, Lyons JM, Damyanova KB, De Oliveira CS, Mabotuwana NS, Stanger SJ, Kaiko GE, Ying TH, Oatley JM, Skillen NM, Lochrin AJ, Peters JL, Lord T
iScience, 26(12):108424, 09 Nov 2023
Cited by: 2 articles | PMID: 38077147 | PMCID: PMC10700845
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
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Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection.
Sikder MAA, Rashid RB, Ahmed T, Sebina I, Howard DR, Ullah MA, Rahman MM, Lynch JP, Curren B, Werder RB, Simpson J, Bissell A, Morrison M, Walpole C, Radford KJ, Kumar V, Woodruff TM, Ying TH, Ali A, [...] Phipps S
Immunity, 56(5):1098-1114.e10, 31 Mar 2023
Cited by: 9 articles | PMID: 37003256
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The maternal microbiome regulates infant respiratory disease susceptibility via intestinal Flt3L expression and plasmacytoid dendritic cell hematopoiesis
Sikder MAA, Rashid RB, Ahmed T, Sebina I, Howard D, Ullah MA, Rahman MM, Lynch JP, Curren B, Werder RB, Simpson J, Bissell A, Morrison M, Walpole C, Radford KJ, Kumar V, Woodruff TM, HuiYing T, Ali A, [...] Phipps S
bioRxiv, 06 Jan 2023
Cited by: 0 articles | PPR: PPR593497
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Enteric nervous system and intestinal epithelial regulation of the gut-brain axis.
Dowling LR, Strazzari MR, Keely S, Kaiko GE
J Allergy Clin Immunol, 150(3):513-522, 01 Sep 2022
Cited by: 21 articles | PMID: 36075637
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Single cell RNA-seq identifies inflammation-induced loss of CFTR-expressing airway ionocytes in non-eosinophilic asthma
Chen L, Hoefel GA, Pathinayake PS, Reid A, Kelly C, HuiYing T, Kim RY, Hansbro PM, Brody SL, Foster PS, Horvat JC, Riveros C, Wark PA, Kaiko GE
bioRxiv, 27 Apr 2022
Cited by: 0 articles | PPR: PPR486717
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Defects in NLRP6, autophagy and goblet cell homeostasis are associated with reduced duodenal CRH receptor 2 expression in patients with functional dyspepsia.
Bruce JK, Burns GL, Sinn Soh W, Nair PM, Sherwin S, Fan K, Dowling LR, Goggins BJ, Koloski N, Potter M, Bollipo S, Foster R, Gan LT, Veysey M, Philpott DJ, Girardin SE, Holtmann G, Kaiko GE, Walker MM, [...] Keely S
Brain Behav Immun, 101:335-345, 31 Jan 2022
Cited by: 6 articles | PMID: 35093492
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Mining the Microbiome and Microbiota-Derived Molecules in Inflammatory Bowel Disease.
Bekkers M, Stojkovic B, Kaiko GE
Int J Mol Sci, 22(20):11243, 18 Oct 2021
Cited by: 5 articles | PMID: 34681902 | PMCID: PMC8540913
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
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T-helper 22 cells develop as a distinct lineage from Th17 cells during bacterial infection and phenotypic stability is regulated by T-bet.
Barnes JL, Plank MW, Asquith K, Maltby S, Sabino LR, Kaiko GE, Lochrin A, Horvat JC, Mayall JR, Kim RY, Hansbro PM, Keely S, Belz GT, Tay HL, Foster PS
Mucosal Immunol, 14(5):1077-1087, 03 Jun 2021
Cited by: 9 articles | PMID: 34083747
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Role of the Intestinal Epithelium and Its Interaction With the Microbiota in Food Allergy.
Ali A, Tan H, Kaiko GE
Front Immunol, 11:604054, 07 Dec 2020
Cited by: 47 articles | PMID: 33365031 | PMCID: PMC7750388
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
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GSTO1-1 is an upstream suppressor of M2 macrophage skewing and HIF-1α-induced eosinophilic airway inflammation.
Sokulsky LA, Goggins B, Sherwin S, Eyers F, Kaiko GE, Board PG, Keely S, Yang M, Foster PS
Clin Exp Allergy, 50(5):609-624, 02 Mar 2020
Cited by: 12 articles | PMID: 32052502
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IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis.
Starkey MR, Plank MW, Casolari P, Papi A, Pavlidis S, Guo Y, Cameron GJM, Haw TJ, Tam A, Obiedat M, Donovan C, Hansbro NG, Nguyen DH, Nair PM, Kim RY, Horvat JC, Kaiko GE, Durum SK, Wark PA, [...] Hansbro PM
Eur Respir J, 54(1):1800174, 18 Jul 2019
Cited by: 40 articles | PMID: 31196943 | PMCID: PMC8132110
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PAI-1 augments mucosal damage in colitis.
Kaiko GE, Chen F, Lai CW, Chiang IL, Perrigoue J, Stojmirović A, Li K, Muegge BD, Jain U, VanDussen KL, Goggins BJ, Keely S, Weaver J, Foster PS, Lawrence DA, Liu TC, Stappenbeck TS
Sci Transl Med, 11(482):eaat0852, 01 Mar 2019
Cited by: 38 articles | PMID: 30842312 | PMCID: PMC6779314
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Isolation and In Vitro Culture of Human Gut Progenitor Cells.
Bruce J, Kaiko GE, Keely S
Methods Mol Biol, 2029:49-62, 01 Jan 2019
Cited by: 0 articles | PMID: 31273733
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Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn's disease.
Liu TC, Kern JT, VanDussen KL, Xiong S, Kaiko GE, Wilen CB, Rajala MW, Caruso R, Holtzman MJ, Gao F, McGovern DP, Nunez G, Head RD, Stappenbeck TS
J Clin Invest, 128(11):5110-5122, 15 Oct 2018
Cited by: 33 articles | PMID: 30137026 | PMCID: PMC6205411
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Developments in cystic fibrosis personalised epithelial assays: Science and patient perspectives.
Kaiko GE, Wark PAB
J Cyst Fibros, 17(3):289-291, 13 Apr 2018
Cited by: 0 articles | PMID: 29661511
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Cellular differentiation: Potential insight into butyrate paradox?
Ryu SH, Kaiko GE, Stappenbeck TS
Mol Cell Oncol, 5(3):e1212685, 27 Feb 2018
Cited by: 10 articles | PMID: 30250879 | PMCID: PMC6150034
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The microbial metabolite desaminotyrosine protects from influenza through type I interferon.
Steed AL, Christophi GP, Kaiko GE, Sun L, Goodwin VM, Jain U, Esaulova E, Artyomov MN, Morales DJ, Holtzman MJ, Boon ACM, Lenschow DJ, Stappenbeck TS
Science, 357(6350):498-502, 01 Aug 2017
Cited by: 280 articles | PMID: 28774928 | PMCID: PMC5753406
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Modeling T_H 2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma.
Foster PS, Maltby S, Rosenberg HF, Tay HL, Hogan SP, Collison AM, Yang M, Kaiko GE, Hansbro PM, Kumar RK, Mattes J
Immunol Rev, 278(1):20-40, 01 Jul 2017
Cited by: 66 articles | PMID: 28658543 | PMCID: PMC5492958
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The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites.
Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM, Stappenbeck TS
Cell, 167(4):1137, 01 Nov 2016
Cited by: 53 articles | PMID: 27814510
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Th22 Cells Form a Distinct Th Lineage from Th17 Cells In Vitro with Unique Transcriptional Properties and Tbet-Dependent Th1 Plasticity.
Plank MW, Kaiko GE, Maltby S, Weaver J, Tay HL, Shen W, Wilson MS, Durum SK, Foster PS
J Immunol, 198(5):2182-2190, 18 Jan 2017
Cited by: 69 articles | PMID: 28100680 | PMCID: PMC5367520
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Harnessing TGF-β and BMP signaling for expansion of p63-positive epithelial stem cells.
Brody SL, Kaiko GE
Stem Cell Investig, 3:82, 15 Nov 2016
Cited by: 2 articles | PMID: 28066784 | PMCID: PMC5182203
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The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites.
Kaiko GE, Ryu SH, Koues OI, Collins PL, Solnica-Krezel L, Pearce EJ, Pearce EL, Oltz EM, Stappenbeck TS
Cell, 165(7):1708-1720, 02 Jun 2016
Cited by: 319 articles | PMID: 27264604 | PMCID: PMC5026192
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Correction: Antagonism of miR-328 Increases the Antimicrobial Function of Macrophages and Neutrophils and Rapid Clearance of Non-typeable Haemophilus Influenzae (NTHi) from Infected Lung.
Tay HL, Kaiko GE, Plank M, Li J, Maltby S, Essilfie AT, Jarnicki A, Yang M, Mattes J, Hansbro PM, Foster PS
PLoS Pathog, 11(6):e1004956, 24 Jun 2015
Cited by: 2 articles | PMID: 26107387 | PMCID: PMC4479355
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This article is in the Europe PMC Open access subset. Refer to the copyright information in the article for licensing details.
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Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles.
Hickey CA, Kuhn KA, Donermeyer DL, Porter NT, Jin C, Cameron EA, Jung H, Kaiko GE, Wegorzewska M, Malvin NP, Glowacki RW, Hansson GC, Allen PM, Martens EC, Stappenbeck TS
Cell Host Microbe, 17(5):672-680, 01 May 2015
Cited by: 130 articles | PMID: 25974305 | PMCID: PMC4432250
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