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Search life-sciences literature (45,103,589 articles, preprints and more)

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Hypoxia-Driven TGFβ Modulation of Side Population Cells in Breast Cancer: The Potential Role of ERα.
Mallini P, Chen M, Mahkamova K, Lennard TWJ, Pan Y, Wei D, Stemke-Hale K, Kirby JA, Lash GE, Meeson A
Cancers (Basel), 15(4):1108, 09 Feb 2023
Cited by: 2 articles | PMID: 36831452 | PMCID: PMC9954173
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The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF.
Watson IR, Li L, Cabeceiras PK, Mahdavi M, Gutschner T, Genovese G, Wang G, Fang Z, Tepper JM, Stemke-Hale K, Tsai KY, Davies MA, Mills GB, Chin L
Cancer Res, 74(17):4845-4852, 23 Jul 2014
Cited by: 100 articles | PMID: 25056119 | PMCID: PMC4167745
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A comprehensive evaluation of biomarkers predictive of response to PI3K inhibitors and of resistance mechanisms in head and neck squamous cell carcinoma.
Mazumdar T, Byers LA, Ng PK, Mills GB, Peng S, Diao L, Fan YH, Stemke-Hale K, Heymach JV, Myers JN, Glisson BS, Johnson FM
Mol Cancer Ther, 13(11):2738-2750, 05 Sep 2014
Cited by: 55 articles | PMID: 25193510 | PMCID: PMC4221385
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Reversing paclitaxel resistance in ovarian cancer cells via inhibition of the ABCB1 expressing side population.
Eyre R, Harvey I, Stemke-Hale K, Lennard TW, Tyson-Capper A, Meeson AP
Tumour Biol, 35(10):9879-9892, 04 Jul 2014
Cited by: 27 articles | PMID: 24993095
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A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation.
Wiegand KC, Hennessy BT, Leung S, Wang Y, Ju Z, McGahren M, Kalloger SE, Finlayson S, Stemke-Hale K, Lu Y, Zhang F, Anglesio MS, Gilks B, Mills GB, Huntsman DG, Carey MS
BMC Cancer, 14:120, 22 Feb 2014
Cited by: 54 articles | PMID: 24559118 | PMCID: PMC3941949
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Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome.
Overman MJ, Zhang J, Kopetz S, Davies M, Jiang ZQ, Stemke-Hale K, Rümmele P, Pilarsky C, Grützmann R, Hamilton S, Hwang R, Abbruzzese JL, Varadhachary G, Broom B, Wang H
PLoS One, 8(6):e65144, 11 Jun 2013
Cited by: 29 articles | PMID: 23776447 | PMCID: PMC3679143
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Correlations between the dielectric properties and exterior morphology of cells revealed by dielectrophoretic field-flow fractionation.
Gascoyne PR, Shim S, Noshari J, Becker FF, Stemke-Hale K
Electrophoresis, 34(7):1042-1050, 01 Apr 2013
Cited by: 70 articles | PMID: 23172680 | PMCID: PMC3754903
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Dielectrophoresis has broad applicability to marker-free isolation of tumor cells from blood by microfluidic systems.
Shim S, Stemke-Hale K, Noshari J, Becker FF, Gascoyne PR
Biomicrofluidics, 7(1):11808, 16 Jan 2013
Cited by: 49 articles | PMID: 24403990 | PMCID: PMC3562275
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Mutation profiling identifies numerous rare drug targets and distinct mutation patterns in different clinical subtypes of breast cancers.
Santarpia L, Qi Y, Stemke-Hale K, Wang B, Young EJ, Booser DJ, Holmes FA, O'Shaughnessy J, Hellerstedt B, Pippen J, Vidaurre T, Gomez H, Valero V, Hortobagyi GN, Symmans WF, Bottai G, Di Leo A, Gonzalez-Angulo AM, Pusztai L
Breast Cancer Res Treat, 134(1):333-343, 27 Apr 2012
Cited by: 80 articles | PMID: 22538770 | PMCID: PMC3885980
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Antibody-independent isolation of circulating tumor cells by continuous-flow dielectrophoresis.
Shim S, Stemke-Hale K, Tsimberidou AM, Noshari J, Anderson TE, Gascoyne PR
Biomicrofluidics, 7(1):11807, 16 Jan 2013
Cited by: 95 articles | PMID: 24403989 | PMCID: PMC3562332
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Inferring tumour purity and stromal and immune cell admixture from expression data.
Yoshihara K, Shahmoradgoli M, Martínez E, Vegesna R, Kim H, Torres-Garcia W, Treviño V, Shen H, Laird PW, Levine DA, Carter SL, Getz G, Stemke-Hale K, Mills GB, Verhaak RG
Nat Commun, 4:2612, 01 Jan 2013
Cited by: 5064 articles | PMID: 24113773 | PMCID: PMC3826632
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Interactions between tumor cells and microenvironment in breast cancer: a new opportunity for targeted therapy.
Mitra S, Stemke-Hale K, Mills GB, Claerhout S
Cancer Sci, 103(3):400-407, 30 Jan 2012
Cited by: 12 articles | PMID: 22151725 | PMCID: PMC5439106
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Frequency of mutations and polymorphisms in borderline ovarian tumors of known cancer genes.
Stemke-Hale K, Shipman K, Kitsou-Mylona I, de Castro DG, Hird V, Brown R, Flanagan J, Gabra H, Mills GB, Agarwal R, El-Bahrawy M
Mod Pathol, 26(4):544-552, 23 Nov 2012
Cited by: 11 articles | PMID: 23174937 | PMCID: PMC3856435
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Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer.
Liang H, Cheung LW, Li J, Ju Z, Yu S, Stemke-Hale K, Dogruluk T, Lu Y, Liu X, Gu C, Guo W, Scherer SE, Carter H, Westin SN, Dyer MD, Verhaak RG, Zhang F, Karchin R, Liu CG, [...] Mills GB
Genome Res, 22(11):2120-2129, 01 Oct 2012
Cited by: 162 articles | PMID: 23028188 | PMCID: PMC3483541
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Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.
Balko JM, Cook RS, Vaught DB, Kuba MG, Miller TW, Bhola NE, Sanders ME, Granja-Ingram NM, Smith JJ, Meszoely IM, Salter J, Dowsett M, Stemke-Hale K, González-Angulo AM, Mills GB, Pinto JA, Gómez HL, Arteaga CL
Nat Med, 18(7):1052-1059, 01 Jul 2012
Cited by: 157 articles | PMID: 22683778 | PMCID: PMC3693569
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A landscape of driver mutations in melanoma.
Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, [...] Chin L
Cell, 150(2):251-263, 01 Jul 2012
Cited by: 1609 articles | PMID: 22817889 | PMCID: PMC3600117
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Detection algorithm for the validation of human cell lines.
Eltonsy N, Gabisi V, Li X, Russe KB, Mills GB, Stemke-Hale K
Int J Cancer, 131(6):E1024-30, 12 Apr 2012
Cited by: 8 articles | PMID: 22419365 | PMCID: PMC3772516
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Systematic analysis of genotype-specific drug responses in cancer.
Kim N, He N, Kim C, Zhang F, Lu Y, Yu Q, Stemke-Hale K, Greshock J, Wooster R, Yoon S, Mills GB
Int J Cancer, 131(10):2456-2464, 29 Mar 2012
Cited by: 26 articles | PMID: 22422301 | PMCID: PMC4012336
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Breast cancer, side population cells and ABCG2 expression.
Britton KM, Eyre R, Harvey IJ, Stemke-Hale K, Browell D, Lennard TWJ, Meeson AP
Cancer Lett, 323(1):97-105, 17 Apr 2012
Cited by: 74 articles | PMID: 22521545 | PMCID: PMC3880937
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Perifosine plus docetaxel in patients with platinum and taxane resistant or refractory high-grade epithelial ovarian cancer.
Fu S, Hennessy BT, Ng CS, Ju Z, Coombes KR, Wolf JK, Sood AK, Levenback CF, Coleman RL, Kavanagh JJ, Gershenson DM, Markman M, Dice K, Howard A, Li J, Li Y, Stemke-Hale K, Dyer M, Atkinson E, [...] Mills GB
Gynecol Oncol, 126(1):47-53, 06 Apr 2012
Cited by: 43 articles | PMID: 22487539 | PMCID: PMC3738300
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ZNF668 functions as a tumor suppressor by regulating p53 stability and function in breast cancer.
Hu R, Peng G, Dai H, Breuer EK, Stemke-Hale K, Li K, Gonzalez-Angulo AM, Mills GB, Lin SY
Cancer Res, 71(20):6524-6534, 18 Aug 2011
Cited by: 23 articles | PMID: 21852383 | PMCID: PMC3193577
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PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer.
Gonzalez-Angulo AM, Ferrer-Lozano J, Stemke-Hale K, Sahin A, Liu S, Barrera JA, Burgues O, Lluch AM, Chen H, Hortobagyi GN, Mills GB, Meric-Bernstam F
Mol Cancer Ther, 10(6):1093-1101, 13 Apr 2011
Cited by: 154 articles | PMID: 21490305 | PMCID: PMC3112276
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High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability.
Cheung LW, Hennessy BT, Li J, Yu S, Myers AP, Djordjevic B, Lu Y, Stemke-Hale K, Dyer MD, Zhang F, Ju Z, Cantley LC, Scherer SE, Liang H, Lu KH, Broaddus RR, Mills GB
Cancer Discov, 1(2):170-185, 07 Jun 2011
Cited by: 298 articles | PMID: 21984976 | PMCID: PMC3187555
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Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma.
Joseph RW, Sullivan RJ, Harrell R, Stemke-Hale K, Panka D, Manoukian G, Percy A, Bassett RL, Ng CS, Radvanyi L, Hwu P, Atkins MB, Davies MA
J Immunother, 35(1):66-72, 01 Jan 2012
Cited by: 74 articles | PMID: 22130161 | PMCID: PMC3241890
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Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.
Prickett TD, Wei X, Cardenas-Navia I, Teer JK, Lin JC, Walia V, Gartner J, Jiang J, Cherukuri PF, Molinolo A, Davies MA, Gershenwald JE, Stemke-Hale K, Rosenberg SA, Margulies EH, Samuels Y
Nat Genet, 43(11):1119-1126, 25 Sep 2011
Cited by: 107 articles | PMID: 21946352 | PMCID: PMC3376644
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