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Myeloma

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Plasmacytoma
Plasmacytoma

Myeloma multiple o simplemente myeloma es un typo de cancere del cellulas plasmic, un typo de leucocytos que normalment produci anticorpores.[1]

Sovente, in le principio, se notifica nulle symptoma.[2] Postea, dolor ossee, anemia, deficientia renal o infections recurrente pote occurrer.[2] Amyloidose pote esser un complication.[3]

Causas del multiple myeloma remane incognoscite.[4] Le factors de risco include obesitate, exposition al radiations, hereditate e alcun substantias chimic.[5][6][7] Le risco es augmentate in alcun empleos.[8] Es debite al exposition al solventes aromatic que poterea causar myelomas multiple.[9]

Se cura con chemotherapia. Un regimen de chemotherapia que se usa commun es le vincristina, adriamycina e dexamethasona. Le thalidomida, velcade, melphalan, prednisona e interferones etiam es utilisate.

Nota
Nota
  1. "Multiple myeloma" (July 2009). Lancet 374 (9686): 324–339. doi:10.1016/S0140-6736(09)60221-X. PMID 19541364. 
  2. 2,0 2,1 Plasma Cell Neoplasms (Including Multiple Myeloma)—Patient Version (1980-01-01).
  3. Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQ®)–Health Professional Version (July 29, 2016).
  4. (2014) World Cancer Report 2014. World Health Organization, Chapter 5.13. ISBN 978-92-832-0429-9. 
  5. (2014) World Cancer Report 2014. World Health Organization, Chapter 2.3 and 2.6. ISBN 978-92-832-0429-9. 
  6. Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (1980-01-01).
  7. (2013) Ferri's Clinical Advisor 2014 E-Book: 5 Books in 1. Elsevier Health Sciences, 726. ISBN 978-0-323-08431-4. 
  8. "Occupational Exposure and Multiple Myeloma Risk: An Updated Review of Meta-Analyses" (September 2021). Journal of Clinical Medicine 10 (18): 4179. doi:10.3390/jcm10184179. PMID 34575290. 
  9. "Pooled study of occupational exposure to aromatic hydrocarbon solvents and risk of multiple myeloma" (November 2018). Occupational and Environmental Medicine 75 (11): 798–806. doi:10.1136/oemed-2018-105154. PMID 30121582.