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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H3K36 methyltransferase activity
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Accession:GO:0046975 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group to the lysine residue at position 36 of the histone H3 protein.
Synonyms:exact_synonym: histone H3K36 methylase activity;   histone lysine N-methyltransferase activity (H3-K36 specific);   histone methylase activity (H3-K36 specific);   histone methyltransferase activity (H3-K36 specific)


show annotations for term's descendants           Sort by:
histone H3K36 methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ash1l ASH1 like histone lysine methyltransferase enables ISO (PMID:26002201) RGD PMID:26002201 NCBI chr 2:174,346,267...174,483,057
Ensembl chr 2:174,346,150...174,483,055 		JBrowse link
G Nsd1 nuclear receptor binding SET domain protein 1 enables ISO
IBA		 (PMID:20837538), (PMID:21196496)
(PMID:12805229)
GO_REF:0000033		 RGD
GO_Central		 PMID:12805229 PMID:20837538 PMID:21196496 GO_REF:0000033 NCBI chr17:9,311,963...9,426,373
Ensembl chr17:9,315,237...9,425,358 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 enables ISO
IBA		 (PMID:24595546), (PMID:33941880)
GO_REF:0000033		 RGD
GO_Central		 PMID:24595546 PMID:33941880 GO_REF:0000033 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641 		JBrowse link
G Nsd3 nuclear receptor binding SET domain protein 3 enables ISO
IBA		 (PMID:21555454)
GO_REF:0000033		 RGD
GO_Central		 PMID:21555454 GO_REF:0000033 NCBI chr16:66,354,030...66,466,202
Ensembl chr16:66,358,973...66,465,423 		JBrowse link
G Prdm9 PR/SET domain 9 enables ISS
ISO
IBA		 GO_REF:0000024
(PMID:27362481)
GO_REF:0000033
(PMID:24634223)		 UniProt
RGD
GO_Central		 PMID:24634223 PMID:27362481 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:56,505,579...56,525,726
Ensembl chr 1:56,505,579...56,525,652 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase enables ISO
IBA		 (PMID:19141475), (PMID:23043551), (PMID:23325844), (PMID:23622243), (PMID:24843002), (PMID:26002201), (PMID:27474439), (PMID:28753426)
MGI:4437211 (PMID:18157086), (PMID:20133625), (PMID:24036311), (PMID:25242323)
GO_REF:0000033		 RGD
GO_Central		 PMID:18157086 PMID:19141475 PMID:20133625 PMID:23043551 PMID:23325844 More... GO_REF:0000033 NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Setd3 SET domain containing 3, actin N3(tau)-histidine methyltransferase enables IBA
ISO		 GO_REF:0000033
(PMID:21832073)		 GO_Central
RGD		 PMID:21832073 GO_REF:0000033 NCBI chr 6:127,023,058...127,090,020
Ensembl chr 6:127,023,058...127,090,008 		JBrowse link
G Setd4 SET domain containing 4 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:32,829,509...32,859,162
Ensembl chr11:32,838,063...32,858,243 		JBrowse link
G Setd5 SET domain containing 5 enables ISO (PMID:31515109) RGD PMID:31515109 NCBI chr 4:146,217,172...146,294,896
Ensembl chr 4:146,217,180...146,294,894 		JBrowse link
G Setmar SET domain and mariner transposase fusion gene enables ISO (PMID:21187428), (PMID:22231448) RGD PMID:21187428 PMID:22231448 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197 		JBrowse link
G Smyd2 SET and MYND domain containing 2 enables ISS
ISO		 GO_REF:0000024
(PMID:16805913), (PMID:22862948)		 UniProt
RGD		 PMID:16805913 PMID:22862948 GO_REF:0000024 NCBI chr13:101,425,270...101,466,576
Ensembl chr13:101,425,273...101,466,576 		JBrowse link
histone H3K36 dimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Setmar SET domain and mariner transposase fusion gene enables ISS
ISO		 GO_REF:0000024
(PMID:16332963)		 UniProt
RGD		 PMID:16332963 GO_REF:0000024 NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197 		JBrowse link
G Smyd3 SET and MYND domain containing 3 enables ISO (PMID:16805913) RGD PMID:16805913 NCBI chr13:90,709,263...91,266,209
Ensembl chr13:90,709,270...91,266,253 		JBrowse link
histone H3K36 trimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nsd2 nuclear receptor binding SET domain protein 2 enables ISO (PMID:19483677) RGD PMID:19483677 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641 		JBrowse link
G Prdm9 PR/SET domain 9 enables IEA GO_REF:0000003
GO_REF:0000116		 UniProt
RHEA		 GO_REF:0000003 GO_REF:0000116 NCBI chr 1:56,505,579...56,525,726
Ensembl chr 1:56,505,579...56,525,652 		JBrowse link
G Setd2 SET domain containing 2, histone lysine methyltransferase enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 8:110,511,808...110,597,475
Ensembl chr 8:110,511,772...110,597,489 		JBrowse link
G Smyd5 SMYD family member 5 enables IEA
ISO		 GO_REF:0000107
(PMID:35680905), (PMID:39083378)		 Ensembl
RGD		 PMID:35680905 PMID:39083378 GO_REF:0000107 NCBI chr 4:117,969,615...117,984,082
Ensembl chr 4:117,969,626...117,984,347 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20627
    catalytic activity 6029
      catalytic activity, acting on a protein 2508
        protein methyltransferase activity 104
          protein-lysine N-methyltransferase activity 69
            histone H3K36 methyltransferase activity 13
              histone H3K36 dimethyltransferase activity 2
              histone H3K36 trimethyltransferase activity 4
Path 2
Term Annotations click to browse term
  molecular_function 20627
    catalytic activity 6029
      transferase activity 2396
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 203
            S-adenosylmethionine-dependent methyltransferase activity 169
              lysine N-methyltransferase activity 69
                protein-lysine N-methyltransferase activity 69
                  histone H3K36 methyltransferase activity 13
                    histone H3K36 dimethyltransferase activity 2
                    histone H3K36 trimethyltransferase activity 4
paths to the root