Alanin transaminaza
| Alanin transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.2 | ||||||||
| CAS broj | 9000-86-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Alanin transaminaza (EC 2.6.1.2, glutaminska piruvinska transaminaza, glutaminska alaninska transaminaza, GPT, beta-alaninska aminotransferaza, alaninska aminotransferaza, alanin-alfa-ketoglutaratna aminotransferaza, alanin-piruvatna aminotransferaza, ALT, glutaminska kiselina-piruvinska kiselina transaminaza, glutaminska-piruvinska aminotransferaza, L-alaninska aminotransferaza, L-alaninska transaminaza, L-alanin-alfa-ketoglutaratna aminotransferaza, piruvatna transaminaza, piruvat-alaninska aminotransferaza, piruvat-glutamatna transaminaza) je enzim sa sistematskim imenom L-alanin:2-oksoglutarat aminotransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim je piridoksal-fosfatni protein.
- ↑ Dumitru, I.F., Iordachescu, D. and Niculescu, S. (1970). „Chromatographic purification, crystallization and study of vegetable L-alanine: 2-oxoglutarate-aminotransferase properties”. Experientia 26: 837-838. PMID 5452003.
- ↑ Dumitru, I.F., Iordachescu, D. and Niculescu, S. (1970). „L-Alanine: 2-oxoglutarate-aminotransferase chromatographic purification and crystallization of the enzyme from seeds of Glycine hispida var Cheepeura”. Rev. Roum. Biochim. 7: 31-44.
- ↑ Green, D.E., Leloir, L.F. and Nocito, W. (1945). „Transaminases”. J. Biol. Chem. 161: 559-582.
- ↑ Iordachescu, D., Dumitru, I.F. and Corniciuc, M.-T. (1983). „Comparative biochemical studies concerning L-alanine: 2-oxoglutarate-aminotransferase from the liver and the bile of swines”. Rev. Roum. Biochim. 20: 173-179.
- ↑ Wilson, D.G., King, K.W. and Burris, R.H. (1954). „Transaminase reactions in plants”. J. Biol. Chem. 208: 863-874. PMID 13174595.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
