UDP-N-acetilgalaktozamin difosforilaza
| UDP-N-acetilgalaktozamin difosforilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.83 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
UDP-N-acetilgalaktozamin difosforilaza (EC 2.7.7.83, UDP-N-acetylgalactosamine diphosphorylase) je enzim sa sistematskim imenom UTP:N-acetil-alfa-D-galaktozamin-1-fosfat uridililtransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UTP + N-acetil-alfa-D-galaktozamin 1-fosfat difosfat + UDP-N-acetil-alfa-D-galaktozamin
Enzim biljki i životinja takođe deluje na N-acetil-alfa-D-glukozamin 1-fosfat.
- ↑ Wang-Gillam, A., Pastuszak, I. and Elbein, A.D. (1998). „A 17-amino acid insert changes UDP-N-acetylhexosamine pyrophosphorylase specificity from UDP-GalNAc to UDP-GlcNAc”. J. Biol. Chem. 273: 27055-27057. PMID 9765219.
- ↑ Peneff, C., Ferrari, P., Charrier, V., Taburet, Y., Monnier, C., Zamboni, V., Winter, J., Harnois, M., Fassy, F. and Bourne, Y. (2001). „Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture”. EMBO J. 20: 6191-6202. PMID 11707391.
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