FUT5

FUT5
Identifikatori
Alijasi	FUT5
Spoljašnji ID	OMIM: 136835 HomoloGene: 134030 GeneCards: FUT5
Obrazac RNK izražavanja
	; ;
	More reference expression data
Genska ontologija
Molecular function	• transferase activity; • alpha-(1->3)-fucosyltransferase activity; • 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; • glycosyltransferase activity; • fucosyltransferase activity;
Cellular component	• саставни део мембране; • Golgi cisterna membrane; • Голџијев апарат; • мембрана; • Golgi membrane;
Biological process	• GO:0033578, GO:0033577, GO:0033575, GO:0033576 protein glycosylation; • L-fucose catabolic process; • fucosylation; • ceramide metabolic process; • Метаболизам угљених хидрата;
	Sources:Amigo / QuickGO
Ortolozi
	2527
	n/a
	ENSG00000130383
	n/a
	Q11128
	n/a
	NM_002034
	n/a
	NP_002025
	n/a
	Wikidata
View/Edit Human

Alfa-(1,3)-fukoziltransferaza je enzim koji je kod ljudi kodiran genom FUT5.^[2]^[3]

Reference

^ „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Weston BW, Nair RP, Larsen RD, Lowe JB (фебруар 1992). „Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities”. The Journal of Biological Chemistry. 267 (6): 4152—60. PMID 1740457. doi:10.1016/S0021-9258(19)50641-X .
^ „Entrez Gene: FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)”.

Literatura

Chiu PC, Chung MK, Koistinen R, Koistinen H, Seppala M, Ho PC, Ng EH, Lee KF, Yeung WS (јануар 2007). „Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding”. Journal of Cell Science. 120 (Pt 1): 33—44. PMID 17148576. doi:10.1242/jcs.03258 . hdl:10722/45488 .
Inaba Y, Ohyama C, Kato T, Satoh M, Saito H, Hagisawa S, Takahashi T, Endoh M, Fukuda MN, Arai Y, Fukuda M (децембар 2003). „Gene transfer of alpha1,3-fucosyltransferase increases tumor growth of the PC-3 human prostate cancer cell line through enhanced adhesion to prostatic stromal cells”. International Journal of Cancer. 107 (6): 949—57. PMID 14601054. S2CID 7078688. doi:10.1002/ijc.11513 .
Roos C, Kolmer M, Mattila P, Renkonen R (фебруар 2002). „Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism”. The Journal of Biological Chemistry. 277 (5): 3168—75. PMID 11698403. doi:10.1074/jbc.M107927200 .
Nishihara S, Iwasaki H, Kaneko M, Tawada A, Ito M, Narimatsu H (децембар 1999). „Alpha1,3-fucosyltransferase 9 (FUT9; Fuc-TIX) preferentially fucosylates the distal GlcNAc residue of polylactosamine chain while the other four alpha1,3FUT members preferentially fucosylate the inner GlcNAc residue”. FEBS Letters. 462 (3): 289—94. PMID 10622713. S2CID 37842289. doi:10.1016/S0014-5793(99)01549-5 .
McCurley RS, Recinos A, Olsen AS, Gingrich JC, Szczepaniak D, Cameron HS, Krauss R, Weston BW (март 1995). „Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21”. Genomics. 26 (1): 142—6. PMID 7782074. doi:10.1016/0888-7543(95)80094-3.
Cameron HS, Szczepaniak D, Weston BW (август 1995). „Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms”. The Journal of Biological Chemistry. 270 (34): 20112—22. PMID 7650030. doi:10.1074/jbc.270.34.20112 .
Weston BW, Smith PL, Kelly RJ, Lowe JB (децембар 1992). „Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes”. The Journal of Biological Chemistry. 267 (34): 24575—84. PMID 1339443. doi:10.1016/S0021-9258(18)35803-4 .

[1] „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1740457-2] Weston BW, Nair RP, Larsen RD, Lowe JB (фебруар 1992). „Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities”. The Journal of Biological Chemistry. 267 (6): 4152—60. PMID 1740457. doi:10.1016/S0021-9258(19)50641-X .

[entrez-3] „Entrez Gene: FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase)”.

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