4′-Fluorococaine

4′-Fluorococaine

Legal status
Legal status	UK: Under Psychoactive Substances Act US: Schedule II
Identifiers
IUPAC name methyl (1R,2R,3S,5S)-3-(4-fluorobenzoyloxy)-8-methyl-8-azabicyclo[3.2.1] octane-2-carboxylate
CAS Number	134507-62-3
PubChem CID	126112
ChemSpider	112124 Y
UNII	6045353J3C
CompTox Dashboard (EPA)	DTXSID10928640
Chemical and physical data
Formula	C17H20FNO4
Molar mass	321.348 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)C3=CC=C(C=C3)F)C(=O)OC
InChI InChI=1S/C17H20FNO4/c1-19-12-7-8-13(19)15(17(21)22-2)14(9-12)23-16(20)10-3-5-11(18)6-4-10/h3-6,12-15H,7-9H2,1-2H3/t12-,13-,14-,15+/m0/s1 Y Key:JRPRINGETIYVSV-ZQDZILKHSA-N Y
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4′-Fluorococaine is a tropane derivative drug which is a synthetic analogue of cocaine. Unlike related compounds such as the corresponding 4′-fluorophenyltropane derivative CFT and the 2′-hydroxy analogue salicylmethylecgonine, 4′-fluorococaine has only around the same potency as cocaine as an inhibitor of dopamine reuptake, but conversely it is a much stronger serotonin reuptake inhibitor than cocaine, resulting in a significantly altered pharmacological profile in animal studies.

See also

• pFBT
• Cocaethylene
• List of cocaine analogues