KEGG   COMPOUND: C00025
Entry
C00025                      Compound                               
Name
L-Glutamate;
L-Glutamic acid;
L-Glutaminic acid;
Glutamate
Formula
C5H9NO4
Exact mass
147.0532
Mol weight
147.13
Structure
Remark
Same as: D00007
Reaction
R00021 R00093 R00114 R00239 R00243 R00245 R00248 R00250
R00251 R00253 R00254 R00256 R00257 R00258 R00259 R00260
R00261 R00262 R00263 R00355 R00372 R00411 R00457 R00494
R00525 R00573 R00575 R00578 R00609 R00667 R00668 R00684
R00694 R00707 R00708 R00734 R00768 R00894 R00895 R00908
R00942 R00986 R01072 R01090 R01155 R01161 R01214 R01231
R01339 R01585 R01586 R01648 R01654 R01684 R01716 R01939
R01956 R02040 R02077 R02199 R02237 R02274 R02282 R02283
R02285 R02287 R02313 R02315 R02433 R02619 R02700 R02772
R02773 R02929 R02930 R03053 R03120 R03189 R03207 R03243
R03266 R03651 R03905 R03916 R03952 R03970 R03971 R04028
R04029 R04051 R04171 R04173 R04188 R04212 R04217 R04234
R04241 R04242 R04269 R04338 R04438 R04463 R04467 R04475
R04529 R04558 R04776 R05052 R05085 R05197 R05207 R05224
R05225 R05507 R05578 R05815 R06423 R06426 R06586 R06631
R06634 R06977 R07275 R07276 R07277 R07396 R07414 R07419
R07456 R07613 R07643 R07659 R08244 R08855 R08897 R08903
R08905 R08906 R08931 R08956 R09195 R09399 R09400 R09401
R09495 R09594 R09598 R09599 R09778 R09824 R09825 R09875
R10086 R10089 R10094 R10141 R10153 R10460 R10677 R10678
R10679 R10687 R10688 R10693 R10698 R10772 R10845 R10902
R10929 R10932 R10991 R10993 R11021 R11118 R11269 R11270
R11285 R11291 R11297 R11298 R11299 R11395 R11409 R11475
R11515 R11561 R11607 R11627 R11705 R11792 R11793 R11794
R11795 R11960 R11963 R12214 R12251 R12272 R12352 R12410
R12412 R12590 R12606 R12663 R12688 R12728 R12730 R12906
R12936 R12939 R13098 R13148 R13305
 » show all
Pathway
map00220  Arginine biosynthesis
map00250  Alanine, aspartate and glutamate metabolism
map00330  Arginine and proline metabolism
map00332  Carbapenem biosynthesis
map00340  Histidine metabolism
map00430  Taurine and hypotaurine metabolism
map00470  D-Amino acid metabolism
map00480  Glutathione metabolism
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map00630  Glyoxylate and dicarboxylate metabolism
map00650  Butanoate metabolism
map00660  C5-Branched dibasic acid metabolism
map00860  Porphyrin metabolism
map00910  Nitrogen metabolism
map00970  Aminoacyl-tRNA biosynthesis
map00997  Biosynthesis of various other secondary metabolites
map00998  Biosynthesis of various antibiotics
map01060  Biosynthesis of plant secondary metabolites
map01064  Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
map01240  Biosynthesis of cofactors
map02010  ABC transporters
map02020  Two-component system
map04068  FoxO signaling pathway
map04072  Phospholipase D signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04216  Ferroptosis
map04540  Gap junction
map04713  Circadian entrainment
map04720  Long-term potentiation
map04721  Synaptic vesicle cycle
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04727  GABAergic synapse
map04730  Long-term depression
map04742  Taste transduction
map04964  Proximal tubule bicarbonate reclamation
map04974  Protein digestion and absorption
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05022  Pathways of neurodegeneration - multiple diseases
map05030  Cocaine addiction
map05031  Amphetamine addiction
map05033  Nicotine addiction
map05034  Alcoholism
map05230  Central carbon metabolism in cancer
Module
M00015  Proline biosynthesis, glutamate => proline
M00027  GABA (gamma-Aminobutyrate) shunt
M00028  Ornithine biosynthesis, glutamate => ornithine
M00045  Histidine degradation, histidine => N-formiminoglutamate => glutamate
M00118  Glutathione biosynthesis, glutamate => glutathione
M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
M00532  Photorespiration
M00740  Methylaspartate cycle
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
M00845  Arginine biosynthesis, glutamate => acetylcitrulline => arginine
M00879  Arginine succinyltransferase pathway, arginine => glutamate
M00970  Proline degradation, proline => glutamate
Network
nt06010  Urea cycle
nt06026  Glutathione biosynthesis
nt06033  Glycine, serine and arginine metabolism
nt06037  Histidine metabolism
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06462  Spinocerebellar ataxia
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06525  Ferroptosis
nt06528  Calcium signaling
Enzyme
1.2.1.88        1.4.1.2         1.4.1.3         1.4.1.4         
1.4.1.13        1.4.1.14        1.4.3.11        1.4.7.1         
1.5.1.9         1.5.1.10        1.5.3.18        1.5.99.5        
1.14.11.76      2.1.1.21        2.1.2.5         2.3.1.1         
2.3.1.14        2.3.1.35        2.3.2.2         2.3.2.-         
2.4.2.14        2.5.1.140       2.6.1.1         2.6.1.2         
2.6.1.3         2.6.1.4         2.6.1.5         2.6.1.6         
2.6.1.7         2.6.1.9         2.6.1.11        2.6.1.13        
2.6.1.16        2.6.1.17        2.6.1.19        2.6.1.22        
2.6.1.23        2.6.1.24        2.6.1.26        2.6.1.27        
2.6.1.29        2.6.1.33        2.6.1.34        2.6.1.36        
2.6.1.38        2.6.1.39        2.6.1.42        2.6.1.44        
2.6.1.48        2.6.1.49        2.6.1.52        2.6.1.55        
2.6.1.57        2.6.1.59        2.6.1.65        2.6.1.67        
2.6.1.72        2.6.1.75        2.6.1.76        2.6.1.79        
2.6.1.80        2.6.1.81        2.6.1.82        2.6.1.83        
2.6.1.85        2.6.1.86        2.6.1.87        2.6.1.89        
2.6.1.90        2.6.1.92        2.6.1.93        2.6.1.94        
2.6.1.95        2.6.1.98        2.6.1.102       2.6.1.103       
2.6.1.104       2.6.1.106       2.6.1.107       2.6.1.109       
2.6.1.110       2.6.1.111       2.6.1.114       2.6.1.116       
2.6.1.118       2.6.1.120       2.6.1.122       2.6.1.123       
2.6.1.125       2.6.1.-         2.7.2.11        3.4.17.21       
3.4.19.9        3.4.19.13       3.4.19.14       3.4.19.16       
3.5.1.2         3.5.1.38        3.5.1.55        3.5.1.65        
3.5.1.68        3.5.1.87        3.5.1.94        3.5.1.96        
3.5.1.118       3.5.1.123       3.5.1.129       3.5.2.9         
3.5.3.8         4.1.1.15        4.1.3.27        4.2.1.168       
4.3.2.10        4.3.3.6         5.1.1.3         5.4.3.9         
5.4.99.1        6.1.1.17        6.1.1.24        6.2.1.39        
6.2.1.68        6.3.1.2         6.3.1.6         6.3.1.11        
6.3.1.17        6.3.1.18        6.3.2.2         6.3.2.12        
6.3.2.17        6.3.2.18        6.3.2.31        6.3.2.32        
6.3.2.33        6.3.2.34        6.3.2.41        6.3.2.42        
6.3.2.53        6.3.2.60        6.3.2.-         6.3.4.2         
6.3.4.12        6.3.4.24        6.3.5.1         6.3.5.2         
6.3.5.3         6.3.5.4         6.3.5.5         6.3.5.6         
6.3.5.7         6.3.5.9         6.3.5.10        6.3.5.11        
6.3.5.12        6.3.5.13        6.3.5.-
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00025  Glutamic acid (Glu)
 Hormones and transmitters
  Neurotransmitters
   Amino acids
    C00025  Glutamate
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Glutamic acid
    D00007  Glutamic acid (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00007  L-Glutamic acid
Other DBs
CAS: 56-86-0
PubChem: 3327
ChEBI: 16015
KNApSAcK: C00001358
PDB-CCD: GGL[PDBj] GLU[PDBj]
NIKKAJI: J9.171E
LinkDB
KCF data

ATOM        10
            1   C1c C    23.8372  -17.4608
            2   C1b C    25.0252  -16.7233
            3   C6a C    22.6023  -16.7994
            4   N1a N    23.8781  -18.8595
            5   C1b C    26.2601  -17.3788
            6   O6a O    21.4434  -17.5954
            7   O6a O    22.6198  -15.4007
            8   C6a C    27.4482  -16.6414
            9   O6a O    28.6830  -17.3028
            10  O6a O    27.4714  -15.2426
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 1
            9     8  10 2

» Japanese version

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