KEGG   REACTION: R02843
Entry
R02843                      Reaction                               
Name
steroid,reduced ferredoxin:oxygen oxidoreductase (11-hydroxylating)
Definition
11-Deoxycortisol + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Cortisol + 2 Oxidized ferredoxin + H2O
Equation
C05488 + 2 C00138 + C00007 + 2 C00080 <=> C00735 + 2 C00139 + C00001
Reaction class
RC00661  C00735_C05488
Enzyme
1.14.15.4
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4
     R02843  11-Deoxycortisol + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Cortisol + 2 Oxidized ferredoxin + H2O
Orthology
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
K07433  steroid 11beta-monooxygenase / corticosterone 18-monooxygenase [EC:1.14.15.4 1.14.15.5]
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