KEGG   Apis mellifera (honey bee): 550749
Entry
550749            CDS       T01057                                 
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic isoform X1
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
ame  Apis mellifera (honey bee)
Pathway
ame00670  One carbon pool by folate
ame01100  Metabolic pathways
ame01240  Biosynthesis of cofactors
ame04981  Folate transport and metabolism
Module
ame_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:ame00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    550749
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    550749
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ame04147]
    550749
Enzymes [BR:ame01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     550749
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     550749
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     550749
Exosome [BR:ame04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   550749
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 550749
NCBI-ProteinID: XP_026296472
BEEBASE: GB48881
UniProt: A0A7M7MGT3
LinkDB
Position
LG5:complement(3001133..3007290)
AA seq 937 aa
MSTDVRGIVLSGTELAKKIRENITKDVKALKEKISNFVPNLAIVQVGGREDSNVYIRMKI
KAANDIGIIVDHVKLPNTITEIELINKVNKLNQDPNIHGIIVQMPLDSVNKINSNMITDL
VLPEKDVDGLNTINEGRVAIGDMSGFLPCTPNGCIELIKKSGVPIAGAQAVVLGRSKIVG
TPISELLKWHNATVTVCHSKTKNLPQIVSQADILVVGIGQPQMVKGNWIKPGAVVIDCGI
NSIPDSTKNNGQRLVGDVDYKEAVKIASYITPVPGGVGPMTVAMLMKNTVISAQRAAEKI
LNKKWKLRILKINPQKPVPSDITISRNQEPKPITILAEEIGLLPNEISPYGSKKAKISLN
VLKRLKHQPNGKLVVVAGITPTPFGEGKSTTSVGLVQALTAHRDKNSFVTLRQPSQGPTF
GVKGGAAGGGYSQVIPMEEFNLHLTGDIHAVTAANNLLAAQIDARYFHECTQTDEALYNR
LVPTIKNERKFSKIQLKRLKKLGITKTDPNSLTEEEKRKFARLDIDPENITWTRVVDIND
RFLRKITIGENPTEKGKTRQTSFCISVGSEIMAILALSTNVDDMKQRLGNIVVAFNKNGE
PLTAEDFGMTGAMAILLKDAIEPTLMQTLEGTPVMVHTGPFANIAHGCSSIIADAIALKL
VGPEGIVVTEAGFGSDIGMEKFFNIKCRASRHVPNAIVLVATVRALKMHGGGPPVTTGAP
LRKEYLEENLDLIRKGLPNLQKHISNGIKFGIPVIVAINVHTTDTQSELELIKEAAIKSG
AIDAIVCNHWAEGGAGATALADAVIAATNKNYNFKVLYDLNINIEEKINIIAKEIYGAGQ
VILADKVQKKIEKYNKLGYDTLPLCMAKTSNSLTGDPSIKGAPIDFTLNITDIFVSVGAG
FIVPMVGEIMMMPGLSTRPSIYDMDWNNETNEIEGLF
NT seq 2814 nt   +upstreamnt  +downstreamnt
atgtcgacagatgtacgaggaattgtattatccggcactgaattagcaaagaaaattcgt
gaaaacataacaaaagatgtgaaagcattgaaagaaaaaatatcaaactttgtacctaat
ttagcgatcgttcaagtaggcggtcgagaagattcaaatgtttacataagaatgaaaata
aaagcagcaaatgatattggaattattgtagatcatgtgaaattaccaaatactatcaca
gaaatagaattaataaacaaagtgaataaattaaatcaagatccaaatatacatggtatt
attgtacaaatgccacttgattctgtcaataaaattaattcaaatatgattactgattta
gtattacccgaaaaagatgtagatggattgaatacaattaatgaaggaagagtagcaatt
ggtgatatgtcgggatttttaccatgcacaccaaatgggtgtattgaattaatcaaaaag
agcggtgtaccaatcgcaggagctcaagctgtagttttaggtagaagtaaaatcgttggt
acacctatatctgaacttttgaaatggcataacgcaaccgtaacagtgtgccattcaaaa
acaaaaaatcttccacaaattgtctcacaagctgatatcttagtagttggtatagggcaa
cctcagatggttaaaggaaattggattaaaccgggcgcagttgtaattgattgtggaatt
aattctattccagactctacaaagaataatggacaacgtttagtgggcgatgttgattac
aaagaagctgtgaaaatagcttcatatattacgcctgtacctggaggcgttggtccaatg
actgtagctatgttgatgaaaaatacagtaatatctgcacaaagagcagctgaaaaaata
ttaaacaaaaaatggaaactgagaattttaaaaatcaaccctcaaaaaccggtacctagc
gacataacaatttcaagaaatcaagaacctaaaccaatcacgattttagctgaagaaatt
ggtttgctccctaatgaaatcagtccttatggaagtaaaaaagcaaagattagcttgaat
gttttaaaacgattgaaacatcaaccaaatggaaaactcgtagtggttgctggtatcaca
ccaacaccttttggtgaaggtaaaagtacgacatcagtaggtttagtgcaagcattaact
gcacacagagataaaaactcatttgtaactttacggcaacctagtcaaggacctacattt
ggagtgaaaggtggagctgcaggtggaggatactcgcaggtcattcccatggaagaattt
aatttacatttaactggtgatattcatgctgtgactgcagccaataatttattagcagca
caaatcgatgctcgatattttcacgagtgtactcaaaccgatgaggctctttataatcgt
cttgtaccaacaattaaaaatgaaagaaaattttcaaaaatacaattgaaacgtttaaaa
aaactaggtattacaaaaactgatccaaatagtttaactgaagaagaaaaaagaaaattt
gcaagattagatatcgatccagaaaatatcacttggactcgagtggttgatataaatgat
cgatttttacgcaaaattacaattggtgaaaatccaactgagaaaggtaaaacacgacaa
acatcattttgcatttctgttggttcagaaataatggcaatacttgcattatcaactaat
gtcgatgatatgaaacagagacttggtaatatagtagttgctttcaacaaaaatggagaa
cccttaactgccgaagattttggtatgactggagcaatggcaattctattaaaagatgcc
attgaaccgacgcttatgcaaactttagaaggaacaccagtaatggttcatactgggcca
tttgcaaatatcgcacacggttgtagttctatcattgcggatgctattgcattaaaatta
gttggtcccgaaggtatcgtagtaaccgaagctggattcggttctgatattggaatggaa
aaattctttaatattaaatgtcgggcatctagacatgtaccaaatgctattgtgctggtt
gcaactgttagagcattaaaaatgcatggtggtgggcctccagtaacaactggtgctcca
ttaagaaaagaatatcttgaagaaaatcttgatttaattagaaaaggtcttccaaatctt
cagaagcacattagtaatggaattaaatttggcattccagtaattgttgccattaacgtt
catactactgatacccaatctgaattagaattaataaaagaagctgcaataaaaagtggt
gcaattgatgcaattgtatgtaatcattgggcagaaggtggtgcaggtgctacagcactt
gcagatgcagttatagctgccacaaataaaaattataattttaaagtattatatgatctt
aatattaatattgaagaaaaaataaatatcattgctaaagaaatatatggagctggacaa
gttattcttgcagataaggttcagaaaaaaatcgaaaaatataataaattaggttatgat
acattacctctttgcatggcaaaaacatcaaactctttaactggtgatccatccattaaa
ggtgcacctattgatttcacacttaatattactgatatatttgtatctgtaggagcaggt
tttatagtacctatggtaggagagataatgatgatgccaggtctatctacaaggccaagt
atttatgacatggattggaataatgaaacaaatgaaatagaaggcttattttga

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