KEGG   Bufo bufo (common toad): 120985975
Entry
120985975         CDS       T07950                                 
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
  KO
K05087  insulin-like growth factor 1 receptor [EC:2.7.10.1]
Organism
bbuf  Bufo bufo (common toad)
Pathway
bbuf04010  MAPK signaling pathway
bbuf04068  FoxO signaling pathway
bbuf04114  Oocyte meiosis
bbuf04140  Autophagy - animal
bbuf04144  Endocytosis
bbuf04150  mTOR signaling pathway
bbuf04510  Focal adhesion
bbuf04520  Adherens junction
bbuf04914  Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:bbuf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    120985975 (IGF1R)
   04068 FoxO signaling pathway
    120985975 (IGF1R)
   04150 mTOR signaling pathway
    120985975 (IGF1R)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    120985975 (IGF1R)
   04140 Autophagy - animal
    120985975 (IGF1R)
  09143 Cell growth and death
   04114 Oocyte meiosis
    120985975 (IGF1R)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    120985975 (IGF1R)
   04520 Adherens junction
    120985975 (IGF1R)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    120985975 (IGF1R)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bbuf01001]
    120985975 (IGF1R)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:bbuf04090]
    120985975 (IGF1R)
Enzymes [BR:bbuf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     120985975 (IGF1R)
Protein kinases [BR:bbuf01001]
 Receptor tyrosine kinases (RTK)
  INSR family [OT]
   120985975 (IGF1R)
CD molecules [BR:bbuf04090]
 Proteins
  120985975 (IGF1R)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like fn3 Kinase-like Y_Y_Y Insulin_TMD
Other DBs
NCBI-GeneID: 120985975
NCBI-ProteinID: XP_040270152
LinkDB
Position
1:complement(709334043..709529811)
AA seq 1370 aa
MKAGSGWGAPAWISGVPLLLLLLLCLCPGQCLGPLGGKVCSTSMDIRNDVQELKQLEDCV
VIEGYLQILLISNAKAEDFRNMRFPKLTVITDYLLLFRVSGLESLSDLFPNLTVIRGRNL
FYNYALVIFEMTDLKEIGLYSLRNITRGAIRIEKNSDLCYLSTVDWSLVLEAVYNNYIIG
NKPPKECGDMCPGVMEDRPLCTKTTINNDYMYRCWSADHCQKVCPSECGKLACSDQNECC
HPECLGSCTTPNNDSACVACQHFYYEGRCVPSCPENTYSFEGWRCISLEDCVNVHTLYTG
TNPFIIHNGECIDECPSGYINNGSVFCSPCDGLCPKICDFEEKTIDSVTSAQMLEGCTVL
KGNLLLNIRKGQNIAAELENFLGLIETVTGYVKIHHSHALVSLSFLKSLRYINGENQKDG
FYSFYVLDNNNLQQLWDWSKHNLTIKQGKMYFAFNPRLCLNEIYTMENATGTIGRQNQLD
INRRNNGDMAPCATVTLKFITNSTSKNRILLTWERYKPKDYRDLISFTVYYKEAPVPNVT
EFDGQDACGSNSWNMVDVDLPEKNDQNPGILLQGLKPWTSYAIFVKALTLTMVEDHQIHG
AKSKIVYIRTDASVPSIPLDVISASNSSFQLIVRWKPPSLPNGNLSYYIVRWQQQPQDSY
LYQDNYCSKDKVPNRKYANGTIDMDEENELTKQESGDGPEKGTCCACPKTEAEKKAEKDE
AEYRKVFENFLHNSIFVPRPDRRRRDVFAVGNATLADLTRNGTTQDFLNTSDSEPNEMEY
LFFETKVDHKYQRTVISNLMPFTLYRIDIHSCNHEAERLGCSASNFVFARTMPAVGADNI
PGAVIVEESDDNAIVLKWPEPPHPNGLILMYEIDYKQQGEILSSECVSRQDYYKMGGAKL
TRLNPGNYTVQVRAISLSGNGSWTEMVTFYVKERVVESDNLLHLAVILPVTTLILLVIVS
LIACYVTRKRYNERLGNGVLYASVNPEYFSAAEMYVPDEWEVPREKITMNRELGQGSFGM
VYEGIAKGVVKDEAETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQG
QPTLVIMELMTRGDLKSYLRSLRPDAESNPGQPPPSLKKMIQMAGEIADGMAYLNANKFV
HRDLAARNCMVSEEFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTH
SDVWSFGVVLWEIATLAEQPYHGMSNEQVLRFVMEGGLLEKPDNCPDMLFELMRMCWQYN
PKMRPSFLEIINSIKDEIDPAFREVSFFYSEENKPPDTEELDLEAENMESIPLDPSCTLQ
TSEHLVGHKAENGPGVVVLRASFDERQPYAHMNGGRKNERALPLPQSSAC
NT seq 4113 nt   +upstreamnt  +downstreamnt
atgaaggccggatcgggctggggggctccggcctggatatcgggggtccccctgctccta
ctgctgctgctgtgcctgtgcccgggccagtgcctggggcccctgggtgggaaagtttgc
agtaccagcatggacattcgtaatgacgtacaggagcttaagcaattagaagactgtgtt
gtaattgaaggctacctccagattctgctcatctccaatgccaaggctgaggatttccga
aacatgcggttccccaagctcactgttattacggactatcttttgcttttccgtgtttct
ggccttgaaagcctgagtgacctctttcccaatctgactgtgatccgtggtcgcaatctt
ttttataactatgccttggtcatttttgagatgactgacctgaaggagattgggctatat
agcctgaggaacattactcgtggtgctattcggattgagaagaactctgacttgtgttac
ctttctactgtggattggtcgctggttctggaggctgtttacaacaactatattatcggt
aataagccaccaaaggagtgtggtgacatgtgccccggggtcatggaggataggccactt
tgtacaaaaacaaccatcaacaatgactatatgtaccgctgctggtcagcagatcactgc
cagaaagtgtgccccagcgagtgcgggaagctagcgtgctcggaccagaatgagtgctgc
caccccgaatgcctgggaagctgcaccactccaaacaacgacagcgcttgcgtggcctgc
cagcatttctactacgagggcagatgtgtcccaagctgccctgagaacacctacagcttt
gagggatggcgctgtatctccttggaagactgtgtcaatgtgcacaccttgtatactgga
acgaacccctttattatacacaatggtgaatgcatagacgaatgcccatctgggtatatt
aacaatggcagtgtgttctgcagtccctgtgatgggctctgtccaaaaatctgtgacttt
gaggagaaaaccattgactctgtcacatcagcgcagatgttggaagggtgcaccgtgctg
aaaggaaacctgctgctcaacatccgcaagggccaaaatattgctgcagagctggagaat
ttcctcggcctgatcgagactgtgaccggatatgtgaaaatccaccactcccatgcactg
gtgtcgctatctttcctgaaaagcctgcgctacatcaatggagagaaccagaaggatggg
ttttactcattttatgttctggacaacaacaatcttcagcaactgtgggactggtccaag
cacaacctcaccatcaaacaaggcaagatgtactttgcatttaaccccaggctatgttta
aacgagatctacactatggaaaatgcaactggaaccataggaagacagaaccaactggat
ataaatcgcagaaataatggagatatggctccctgtgcgaccgtcactctgaaattcatc
accaacagcacaagtaagaacagaatactcttgacgtgggagcgttacaagcccaaggat
tatagagacctcatcagcttcactgtctactataaagaagcccctgttcctaatgtgact
gaatttgacggtcaggacgcatgtgggtccaacagttggaacatggtggatgtggacctg
ccagagaaaaatgatcagaacccaggcattcttctgcagggcctgaagccctggacttcc
tatgcaatctttgtaaaagcccttactttgaccatggtggaggaccatcagattcatgga
gccaagagcaaaattgtttacatacgtacagacgcttcagtgccctccattcctctggat
gtcatctctgcctcgaattcatcctttcagctgattgtgaggtggaagcctccctctttg
ccaaatggcaacctctcctattacattgtgcgctggcagcagcagcctcaggacagttac
ctgtaccaagacaactactgctctaaagataaagtccctaatcgaaaatatgctaatggc
accattgacatggatgaagaaaatgagctaacgaagcaagaatcgggagatggaccagaa
aagggaacttgctgcgcttgtcctaaaactgaggctgagaagaaagctgaaaaggatgaa
gcagagtacaggaaggtgtttgagaacttcctgcacaactccatctttgtgccacggcct
gatcgcagacgacgtgacgtgttcgctgttggcaatgcaacactggctgacttgaccaga
aatggcactacacaagacttcttgaacacgtcagactctgaaccgaacgagatggagtat
ctgttttttgagacaaaggtggaccataaataccagagaactgttatctcaaacctgatg
ccatttactctgtaccggatcgatatccacagctgtaaccacgaggcagaaaggcttggc
tgcagcgcttccaactttgtgtttgccagaaccatgcctgcagttggtgcggataacata
cctggagcggtcatcgttgaggaatccgatgataatgccattgtcctgaagtggcctgag
ccccctcatcccaatggactcatcctgatgtatgagattgattacaagcagcagggggag
attctcagcagtgaatgtgtctccagacaagactactataagatgggaggtgccaaactt
accagactaaacccaggcaactatactgtgcaagtgcgagccatatcgctctctggaaat
ggttcctggacggagatggtgactttctatgtgaaggagagagttgttgaaagtgacaat
ctcctgcacctggctgtgattctacccgtcaccacattgattttgcttgtgatcgtctct
ttgatcgcctgctatgttacaaggaagaggtacaatgagcgactaggcaatggagtgtta
tacgcctctgtgaaccctgaatacttcagtgcagcggagatgtatgtgcccgacgaatgg
gaggtgcctcgggagaagataacaatgaaccgcgagctgggacagggatcatttggaatg
gtgtatgaagggattgcaaagggggtggtgaaagatgaagcagaaaccagagtggcgata
aaaactgtgaatgaggccgccagcatgagggaaaggattgagttcttaaacgaggcttcg
gtgatgaaggagttcaactgtcaccatgtggtacgtttgttaggtgtggtttctcaaggc
caaccaacccttgtcatcatggaattaatgactcgtggagacctcaaaagctatttgaga
tctttaagaccagacgcagagagtaaccctgggcagcctcccccttccttgaagaaaatg
atccagatggcaggagagattgcagatgggatggcatatctcaatgcaaataaatttgtt
cacagagacctagcagccagaaactgcatggtgtctgaagaattcacagtcaaaatcgga
gactttggaatgactcgagacatatacgagacagattattatcgaaagggaggaaaaggt
ctccttccagtgcgctggatgtcaccagaatctctcaaagatggtgtcttcaccactcac
tctgatgtctggtcatttggtgtggtcttatgggagatagctacactggctgagcagcca
taccacggcatgtccaatgagcaggtcctccgattcgtcatggaaggaggtctcttggag
aagccagataactgcccagatatgctgtttgagttgatgcgcatgtgctggcaatacaac
cctaaaatgaggccctcattcctggaaataatcaacagcattaaagacgagattgatcca
gcgttcagagaggtgtcgtttttttatagtgaggagaacaaacctccagatacagaggag
ctggacctggaggcagagaacatggagagcattccattggatccatcatgtaccttgcag
acatctgaacatctcgtgggacacaaggctgagaatggcccaggtgtagttgtcttaaga
gcaagctttgatgagcggcaaccatatgcacacatgaatggggggcgcaagaacgagagg
gcactacctctcccccagtcttcagcctgctga

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