KEGG   Coturnix japonica (Japanese quail): 107315290
Entry
107315290         CDS       T04297                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
cjo  Coturnix japonica (Japanese quail)
Pathway
cjo00670  One carbon pool by folate
cjo01100  Metabolic pathways
cjo01240  Biosynthesis of cofactors
cjo04981  Folate transport and metabolism
Module
cjo_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:cjo00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    107315290 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    107315290 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cjo04147]
    107315290 (MTHFD1)
Enzymes [BR:cjo01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     107315290 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     107315290 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     107315290 (MTHFD1)
Exosome [BR:cjo04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   107315290 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH OCD_Mu_crystall DUF6507
Other DBs
NCBI-GeneID: 107315290
NCBI-ProteinID: XP_015720957
LinkDB
Position
5:complement(48137101..48170348)
AA seq 935 aa
MAPAEVLSGKVVSAQVRERLKQQVAEMKEKFPGFTPGLAILQVGNRDDSNLYINMKLKAA
AEIGISANHIKLPNTATEAEVLKCIASLNGDPAVHGFIVQLPLDSDKPINTEKITNAVAP
EKDVDGLSSINAGKLSRGDLGDCFIPCTPKGCMELIRQTGIQVTGKRAVVVGRSKIVGAP
MHDLLLWNHATVTTCHSKTSTLAEEVAKADILVVAAGKAEMVKGEWIKPGAIVIDCGINH
VPDSTKASGKRVVGDVAYATAKEKASYITPVPGGVGPMTVAMLMQSTVESAQRFLEKFQP
GKWNIQYNQLTLKMPVPSDIEISRSCIPKPIDQVAREIGLLPDELELYGQTKAKVHLSAL
KRLKNQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLHQNVFACVRQPSQGPTFGI
KGGAAGGGYSQVVPMEEFNLHLTGDIHAITAANNLVAAALDTRIFHEQTQNDQALYNRLV
PSVNGVRKFSEIQIRRLQKLGINKTDPAALTKEEVNLFVRLDIDPATITWQRVLDTNDRF
LRKITIGQSPTEGGFSRVAQFDITVSSEIMAVLALSDGLDDMKKRLGRMVVASNKRGEPV
TTDDLGVTGALAVLMKDAVKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKVALKLVG
KEGFVVTEAGFGADIGMEKFFNIKCRYSDLRPNVVVLVATVRALKMHGGGPTVSAGVPLP
KEYTEENLQLLAKGCSNLSKQIQNARLFGVPVVVAVNAFKTDTKAELALVVQLAKEAGAF
DAVECTHWAEGGKGAVALARAVQRASQTPSNFRFLYNVELPVIDKIRIIAQQIYGASDIE
LLPEAQEKVAVYTKQGFGNLPICMAKTHLSLSHDPEQKGAPTGFILPIRDIRASVGAGFL
YPLVGKMSTMPGLPTRPSFYDIDLDTTSGEVNGLF
NT seq 2808 nt   +upstreamnt  +downstreamnt
atggcccccgcagaggttctcagcggcaaagtcgtctccgcacaagtgagagagaggtta
aagcagcaagttgctgagatgaaggagaagtttccaggtttcacaccaggactcgcgatt
ttgcaggttggaaatcgggatgactcgaacctctacattaacatgaagctgaaggctgct
gctgagattgggatcagtgccaaccacataaaactaccaaacacagcaacagaagctgag
gtcctcaagtgcattgcttctttgaatggagaccctgctgttcatggcttcatagtgcag
ttgccccttgactctgataaacctatcaatactgaaaaaataaccaatgctgttgcacct
gagaaggatgtagatggcttaagtagcatcaatgctgggaaactgtctagaggagacctt
ggagactgctttattccatgtactccaaaaggatgcatggaacttatcagacagacaggc
attcaggttacggggaaaagagctgtagtggttggtcgcagtaagatcgttggtgctcct
atgcatgacctgctgctctggaatcatgcaacagtaaccacttgccattcaaagacctca
acactggctgaggaggttgctaaagctgatatcctggtggttgcagctggcaaagctgaa
atggtgaaaggtgaatggatcaaacctggtgcaattgtaatagactgtggaattaaccat
gtgccagatagcacaaaggccagtggaaaaagagttgtaggagacgtggcatacgcaaca
gcaaaagagaaagcttcttacattaccccagttcctggtggtgttggaccaatgactgtg
gccatgttaatgcagagtacagtggagagtgcacagcgttttctggagaaattccagcct
ggaaaatggaacatccaatacaaccaacttaccctgaagatgcctgttccaagtgacatt
gaaatatcacggtcttgcatacccaagcccattgatcaagttgcaagagaaattggcctc
ctccctgatgagttagaactgtatggccaaactaaagccaaggttcatctgtcggctctg
aaacgtctgaagaaccagcctgatggcaaatacgttgttgttactgggattactcccaca
cctctgggtgaggggaaaagcaccaccaccataggtcttgttcaagccttaggagcacac
cttcaccagaacgtctttgcttgtgttcggcagccttctcaggggccaacctttgggata
aaaggaggagctgctggtggtggctattctcaagttgttcccatggaagagtttaacctt
cacctcaccggtgacatccacgctatcactgcagcgaacaacttggttgctgctgctttg
gacacacgtatattccatgaacaaactcagaacgaccaggctctctataaccgtttggtg
ccttctgtcaatggagtcaggaagttctcagagattcaaatccgaagactacaaaaattg
ggcattaacaaaactgatcctgcagccttgacgaaggaggaagtgaacttatttgtgaga
ctggacattgacccagctaccataacatggcaaagagtactggatacaaatgacagattc
cttaggaaaatcactattggacagtctccaacagaaggcggcttttcacgagtggctcag
tttgacatcacagtgagcagtgaaatcatggcagttctagcactctctgatggcctggat
gacatgaaaaagcgactgggcagaatggtagtagcttccaacaagagaggagaaccagtt
acaacggatgaccttggagtaacaggtgctttggcagttttgatgaaagatgcagttaag
ccaaacctgatgcagacactagagggaactcctgtgtttgttcatgcgggaccttttgcc
aatattgcacatgggaattcttcagtgttggcagacaaagtagcgctgaagcttgtgggc
aaagagggttttgttgttacagaagcagggtttggcgcagacataggcatggagaagttc
tttaacattaagtgtcgttattctgatctccggcccaatgtggtggtgttggttgctact
gtccgagctctgaaaatgcacggaggagggcctacagtctctgctggggtacctttgcca
aaggagtacacggaggagaatcttcagctgttggcaaaaggttgcagtaacctaagcaaa
caaatccaaaatgctcggctgtttggtgtcccagtagtagtggctgtcaatgctttcaag
acagatacgaaggctgaactggctcttgtagtacaactggcaaaagaagcaggagcattt
gatgctgtggagtgcactcactgggcagagggtggtaaaggagctgttgcattggctcgg
gctgttcagagagcatcacagacacccagcaacttcaggttcctctataatgtagagctt
cctgttatagataaaatcagaattattgcacagcagatctatggggcaagtgacattgag
ctacttccagaagctcaggagaaagtcgccgtgtacactaagcagggctttggaaacctg
ccaatctgcatggctaaaactcacttatcgttgtctcatgaccctgaacaaaaaggagct
cctacaggttttattctgccaatccgagacattcgggccagtgttggtgctgggttcctg
tacccactggtaggaaagatgagcactatgccaggacttcctacaagacccagcttttat
gatattgacttggacaccacgtcgggagaagtgaacgggctcttctga

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