KEGG   Hyaena hyaena (striped hyena): 120235769
Entry
120235769         CDS       T07257                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial isoform X1
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
hhv  Hyaena hyaena (striped hyena)
Pathway
hhv00140  Steroid hormone biosynthesis
hhv01100  Metabolic pathways
hhv04913  Ovarian steroidogenesis
hhv04925  Aldosterone synthesis and secretion
hhv04927  Cortisol synthesis and secretion
hhv04934  Cushing syndrome
Module
hhv_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:hhv00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    120235769
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    120235769
   04925 Aldosterone synthesis and secretion
    120235769
   04927 Cortisol synthesis and secretion
    120235769
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    120235769
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:hhv00199]
    120235769
Enzymes [BR:hhv01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     120235769
Cytochrome P450 [BR:hhv00199]
 Cytochrome P450, animal type
  CYP11 family
   120235769
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 120235769
NCBI-ProteinID: XP_039094168
LinkDB
Position
Unknown
AA seq 520 aa
MLAKGLPLRSALLKGCQSFPNTAREGPGHPWAPTGDGAGISTQIPRPFSEIPSPGNNGWL
NLYNFWREMGSQKIHYYQLQNFQKYGPIYREKLGSMESVYIIDPEDVARLFKFEGPTPER
YSVPPWVAYHQHYQRPLGVLLKKSGAWKKDRLALNQEVMSPEAVKNFIPLLDPVSQDFVK
VLHRRIKTQGSGKFSGVISADLFRFAFESITNVMFGERLGMLEEMVDPEAQRFIDAVYQM
FHTSVPMLTLPPDLFRLFKTKTWKDHVAAWDVIFNKAEIYTHNFYWDLRHKRDFSSYPGI
LHRLLRSNKLLFEDVKANITEMLAGGVDTTSMTLQWHLYEMARSLKVQEMLRKEVLDARR
QAQGNISAMLQQVPLLKASIKETLRLHPISVTLQRYLENDLVLRNYMIPAKTLVQVSTYA
LGQDPTFFLNPGKFDPTRWLNKDKELIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILE
NFRVEIQHLNDVGTTFNLILMPDKPIFFTFRPYTQDPPQV
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgctggcaaaggggctccctcttcgctcagctctgctcaaaggctgccagtccttcccg
aacaccgcacgggagggtccggggcatccctgggcacctactggggacggggccggaatc
tccactcagattcctcgccccttctctgagatcccctcccctggaaacaatggctggcta
aacctgtacaatttctggagggagatgggctcgcagaaaatccactattaccaactccag
aacttccagaagtatggccccatttacagggagaagctgggcagcatggagtcggtttat
atcatcgaccctgaagatgtggcccgtctctttaagttcgagggtcccactccagaacga
tattctgtcccaccctgggtggcctatcaccagcattaccagagacccctcggagtcctg
ttgaagaagtcaggagcttggaagaaagaccgactggccctgaaccaggaggtgatgtct
ccagaggccgtaaagaacttcattcccctgctggacccagtgtctcaggactttgtgaaa
gtcctgcacaggcgcatcaagacgcagggctctggaaagttctcaggggtcatcagtgcc
gacctgtttcgctttgcctttgaatccatcaccaatgtcatgttcggggagcgcctgggg
atgctggaggagatggtggaccccgaggcccagcggttcatcgacgctgtctaccagatg
ttccacacgagtgtccccatgctcaccttacccccagacctgttccgtctgttcaagacc
aagacctggaaggaccatgtggctgcatgggatgtgattttcaataaagcggagatctac
acccataacttctactgggacctgaggcacaagagagatttcagcagttacccgggcatc
ctccaccgcctcctacgaagcaacaagctgctctttgaggatgtcaaggccaatataaca
gagatgttggcagggggtgtggacacgacgtccatgaccctgcagtggcacctgtatgag
atggcccgcagcctgaaggtgcaggagatgttgcggaaagaggtcctggacgcccggcgc
caggcccagggaaacatcagcgcgatgttgcagcaggtccctctgctcaaggccagcatc
aaggagacactgagactccaccccatctcggtgaccctgcagagataccttgagaatgac
ttggttcttcgaaattacatgattcctgccaagacattggtgcaggtgtccacctatgcc
ttgggccaagaccccaccttcttcctcaatccgggcaagttcgacccaacccgatggctg
aataaagacaaggaactcatccacttccggaacctgggctttggctggggtgtgcggcag
tgtgtgggccggcggattgctgagctcgagatgaccctcttcctcatccacattctggag
aacttcagagttgaaattcaacatctcaacgatgtgggcacaacattcaacctcatcctg
atgcctgacaagcccatcttcttcaccttcaggccctacacccaggacccaccccaggtg
tga

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