Nyctereutes procyonoides (raccoon dog): 129510268
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Entry
129510268 CDS
T09008
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
npo
Nyctereutes procyonoides (raccoon dog)
Pathway
npo01521
EGFR tyrosine kinase inhibitor resistance
npo01522
Endocrine resistance
npo04010
MAPK signaling pathway
npo04014
Ras signaling pathway
npo04015
Rap1 signaling pathway
npo04066
HIF-1 signaling pathway
npo04068
FoxO signaling pathway
npo04114
Oocyte meiosis
npo04140
Autophagy - animal
npo04144
Endocytosis
npo04150
mTOR signaling pathway
npo04151
PI3K-Akt signaling pathway
npo04152
AMPK signaling pathway
npo04211
Longevity regulating pathway
npo04213
Longevity regulating pathway - multiple species
npo04510
Focal adhesion
npo04520
Adherens junction
npo04550
Signaling pathways regulating pluripotency of stem cells
npo04730
Long-term depression
npo04913
Ovarian steroidogenesis
npo04914
Progesterone-mediated oocyte maturation
npo05200
Pathways in cancer
npo05202
Transcriptional misregulation in cancer
npo05205
Proteoglycans in cancer
npo05214
Glioma
npo05215
Prostate cancer
npo05218
Melanoma
npo05224
Breast cancer
npo05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
npo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129510268 (IGF1R)
04014 Ras signaling pathway
129510268 (IGF1R)
04015 Rap1 signaling pathway
129510268 (IGF1R)
04066 HIF-1 signaling pathway
129510268 (IGF1R)
04068 FoxO signaling pathway
129510268 (IGF1R)
04151 PI3K-Akt signaling pathway
129510268 (IGF1R)
04152 AMPK signaling pathway
129510268 (IGF1R)
04150 mTOR signaling pathway
129510268 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
129510268 (IGF1R)
04140 Autophagy - animal
129510268 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
129510268 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129510268 (IGF1R)
04520 Adherens junction
129510268 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
129510268 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
129510268 (IGF1R)
04914 Progesterone-mediated oocyte maturation
129510268 (IGF1R)
09156 Nervous system
04730 Long-term depression
129510268 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
129510268 (IGF1R)
04213 Longevity regulating pathway - multiple species
129510268 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129510268 (IGF1R)
05202 Transcriptional misregulation in cancer
129510268 (IGF1R)
05205 Proteoglycans in cancer
129510268 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
129510268 (IGF1R)
05214 Glioma
129510268 (IGF1R)
05218 Melanoma
129510268 (IGF1R)
05215 Prostate cancer
129510268 (IGF1R)
05224 Breast cancer
129510268 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129510268 (IGF1R)
01522 Endocrine resistance
129510268 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
npo01001
]
129510268 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
npo04090
]
129510268 (IGF1R)
Enzymes [BR:
npo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
129510268 (IGF1R)
Protein kinases [BR:
npo01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
129510268 (IGF1R)
CD molecules [BR:
npo04090
]
Proteins
129510268 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
129510268
NCBI-ProteinID:
XP_055182249
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNTTVVDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
RRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRL
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgtttttctcc
gccgcgctgtcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aatgactatcagcagctgaagcgcctggagaactgtacagtgatcgagggctacctccac
atcctactcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgttgttccgtgtggccggccttgagagcctcggggatctcttc
ccgaacctcacggtcatccgtggctggaagctcttctacaactacgccctggtcatcttt
gagatgaccaacctcaaggatattgggctttacaatctgaggaacattactcggggggcc
atcaggattgagaagaatgctgacctctgttacctctccacagtggactggtccctgatc
ctggatgcagtgtccaacaactacatcgtggggaacaaacccccgaaggaatgtggggac
ctgtgtccagggacaatggaggagaagcccttgtgcgagaagactaccatcaacaatgaa
tacaactatcgctgctggactacaaatcgctgccagaaaatgtgcccgagcgcttgcggg
aagcgggcgtgcacagagaacaacgagtgttgtcaccccgagtgtctgggcagctgcagc
gcgccggacaacgatacggcctgtgtggcctgcaggcattactactacgcaggcgtctgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccatgac
ggcgagtgcatgcaggagtgcccctctgggttcatccgcaatggcagtcagagcatgtac
tgcatcccttgtgaaggtccttgtcccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgtaccatcttcaagggcaatttg
ctcattaatatccgccgaggcaataacattgcctcagagctggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattcccatgccttggtctccctgtcc
ttcctaaaaaaccttcgccagatcttaggagaggaacagctggaagggaactactccttc
tacgtcctcgacaaccagaacttgcagcagctttgggattgggaccaccgtaacctgacc
atcaaagctgggaaaatgtattttgctttcaatcccaaattgtgcgtctccgaaatttac
cgcatggaagaagtgacggggaccaaaggacgccagagcaaaggagacataaataccaga
aacaatggagaacgagcctcctgtgaaagcgacgtcctgcacttcacctctacgaccaca
tggaagaatcgcatcatcatcacgtggcaccgttaccggccccctgactacagggatctc
atcagctttactgtctactacaaggaagcaccttttaaaaacgtcacggagtatgatggg
caggatgcctgtggctccaacagctggaatatggtagatgtggacctccctcccaacaag
gacgtcgagcctggcattttactgcacggactgaagccctggacgcagtatgcggtttat
gtcaaggcggtgaccctcaccatggtggagaatgaccacatccgtggggctaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttctgcg
tcaaactcctcttctcagctcattgtgaaatggaacccaccctctctgcccaacggtaac
ctcagttactacatcgtgaggtggcagcggcagccccaggacagttacctttaccgccac
aactactgctccaaagataaaatccccatcaggaagtatgctgatggcaccatcgatgtc
gaagaggtgacagagaatcccaagaccgaagtatgtggtggagagaaggggccttgctgt
gcctgccccaaaaccgaggccgagaagcaggctgagaaggaggaggccgagtaccgcaaa
gtgttcgagaatttcctgcacaactccatctttgtgcccagacctgaaaggaagcgtaga
gatgttacacaagtcaccaacaccaccatgtccagccgaagcaggaacaccacggtggtg
gacacctataatatcacagacccagaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtaatctctaacctccggccttttaccctgtaccgc
attgacatccacagctgcaatcatgaggctgagaagctgggctgcagtgcctccaacttt
gtttttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacctgg
gagtcaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatatggatcccaaatcgaggatcagcgagaatgtgta
tccagacaggagtacaggaagtatggaggtgccaagcttaaccggctcaacccggggaac
tatacagcccggatccaggccacttctctctctgggaatgggtcgtggacggatcctgtg
ttcttctatgtcccagccaaaataacgtatgaaaacttcatccatctgatcattgctctg
cccgttgctgtgctattgatagtgggagggttggttataatgctgtatgtcttccacagg
agaagaaataacagcaggctggggaatggagtgctgtatgcttccgtgaacccagaatac
ttcagtgctgccgatgtgtatgtacctgatgagtgggaggttgctcgagagaagatcacc
atgagccgagagctgggccagggctcatttgggatggtatatgaaggagttgccaagggt
gtggttaaagatgagcctgaaacaagggtggccattaaaacagtgaacgaggccgccagc
atgcgtgaaaggatcgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggtgtggtgtcccagggccagccgacgttggtcatcatggaa
ctgatgacacgaggggatctcaaaagttatctcaggtctctgaggccagaaatagagaat
aatccagtcctcgcacctccaagcctaagcaagatgatccagatggctggggagattgct
gatggcatggcatacctcaacgccaacaagtttgtccacagagaccttgctgccaggaac
tgcatggtggccgaagatttcacagtcaaaattggagatttcggtatgacaagagacatc
tatgagacagactattaccggaaaggaggcaaggggctgctgcctgtgcgctggatgtca
cctgagtctctcaaggatggagtcttcaccactcactctgacgtctggtcctttggggtc
gttctctgggagatcgccacgctggctgagcagccataccagggcttgtccaacgagcaa
gtccttcgcttcgttatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggacctggagccggagaacatg
gagagtgtccccctggacccgtcggcctcctcgtcgtcgctgcctctgcctgacagactc
tcaggacacaaggccgagaacggcccaggccctggcgtgctggtcctgcgagccagcttc
gatgagagacagccttacgcgcacatgaacgggggccgcaagaacgagcgggccttgcct
ctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system