KEGG   Nyctereutes procyonoides (raccoon dog): 129510268
Entry
129510268         CDS       T09008                                 
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
  KO
K05087  insulin-like growth factor 1 receptor [EC:2.7.10.1]
Organism
npo  Nyctereutes procyonoides (raccoon dog)
Pathway
npo01521  EGFR tyrosine kinase inhibitor resistance
npo01522  Endocrine resistance
npo04010  MAPK signaling pathway
npo04014  Ras signaling pathway
npo04015  Rap1 signaling pathway
npo04066  HIF-1 signaling pathway
npo04068  FoxO signaling pathway
npo04114  Oocyte meiosis
npo04140  Autophagy - animal
npo04144  Endocytosis
npo04150  mTOR signaling pathway
npo04151  PI3K-Akt signaling pathway
npo04152  AMPK signaling pathway
npo04211  Longevity regulating pathway
npo04213  Longevity regulating pathway - multiple species
npo04510  Focal adhesion
npo04520  Adherens junction
npo04550  Signaling pathways regulating pluripotency of stem cells
npo04730  Long-term depression
npo04913  Ovarian steroidogenesis
npo04914  Progesterone-mediated oocyte maturation
npo05200  Pathways in cancer
npo05202  Transcriptional misregulation in cancer
npo05205  Proteoglycans in cancer
npo05214  Glioma
npo05215  Prostate cancer
npo05218  Melanoma
npo05224  Breast cancer
npo05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:npo00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    129510268 (IGF1R)
   04014 Ras signaling pathway
    129510268 (IGF1R)
   04015 Rap1 signaling pathway
    129510268 (IGF1R)
   04066 HIF-1 signaling pathway
    129510268 (IGF1R)
   04068 FoxO signaling pathway
    129510268 (IGF1R)
   04151 PI3K-Akt signaling pathway
    129510268 (IGF1R)
   04152 AMPK signaling pathway
    129510268 (IGF1R)
   04150 mTOR signaling pathway
    129510268 (IGF1R)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    129510268 (IGF1R)
   04140 Autophagy - animal
    129510268 (IGF1R)
  09143 Cell growth and death
   04114 Oocyte meiosis
    129510268 (IGF1R)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    129510268 (IGF1R)
   04520 Adherens junction
    129510268 (IGF1R)
   04550 Signaling pathways regulating pluripotency of stem cells
    129510268 (IGF1R)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    129510268 (IGF1R)
   04914 Progesterone-mediated oocyte maturation
    129510268 (IGF1R)
  09156 Nervous system
   04730 Long-term depression
    129510268 (IGF1R)
  09149 Aging
   04211 Longevity regulating pathway
    129510268 (IGF1R)
   04213 Longevity regulating pathway - multiple species
    129510268 (IGF1R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129510268 (IGF1R)
   05202 Transcriptional misregulation in cancer
    129510268 (IGF1R)
   05205 Proteoglycans in cancer
    129510268 (IGF1R)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    129510268 (IGF1R)
   05214 Glioma
    129510268 (IGF1R)
   05218 Melanoma
    129510268 (IGF1R)
   05215 Prostate cancer
    129510268 (IGF1R)
   05224 Breast cancer
    129510268 (IGF1R)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    129510268 (IGF1R)
   01522 Endocrine resistance
    129510268 (IGF1R)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:npo01001]
    129510268 (IGF1R)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:npo04090]
    129510268 (IGF1R)
Enzymes [BR:npo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     129510268 (IGF1R)
Protein kinases [BR:npo01001]
 Receptor tyrosine kinases (RTK)
  INSR family [OT]
   129510268 (IGF1R)
CD molecules [BR:npo04090]
 Proteins
  129510268 (IGF1R)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain Furin-like Pkinase fn3 Kinase-like
Other DBs
NCBI-GeneID: 129510268
NCBI-ProteinID: XP_055182249
LinkDB
Position
Unknown
AA seq 1367 aa
MKSGSGGGSPTSLWGLVFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNTTVVDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
RRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRL
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq 4104 nt   +upstreamnt  +downstreamnt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgtttttctcc
gccgcgctgtcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aatgactatcagcagctgaagcgcctggagaactgtacagtgatcgagggctacctccac
atcctactcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgttgttccgtgtggccggccttgagagcctcggggatctcttc
ccgaacctcacggtcatccgtggctggaagctcttctacaactacgccctggtcatcttt
gagatgaccaacctcaaggatattgggctttacaatctgaggaacattactcggggggcc
atcaggattgagaagaatgctgacctctgttacctctccacagtggactggtccctgatc
ctggatgcagtgtccaacaactacatcgtggggaacaaacccccgaaggaatgtggggac
ctgtgtccagggacaatggaggagaagcccttgtgcgagaagactaccatcaacaatgaa
tacaactatcgctgctggactacaaatcgctgccagaaaatgtgcccgagcgcttgcggg
aagcgggcgtgcacagagaacaacgagtgttgtcaccccgagtgtctgggcagctgcagc
gcgccggacaacgatacggcctgtgtggcctgcaggcattactactacgcaggcgtctgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccatgac
ggcgagtgcatgcaggagtgcccctctgggttcatccgcaatggcagtcagagcatgtac
tgcatcccttgtgaaggtccttgtcccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgtaccatcttcaagggcaatttg
ctcattaatatccgccgaggcaataacattgcctcagagctggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattcccatgccttggtctccctgtcc
ttcctaaaaaaccttcgccagatcttaggagaggaacagctggaagggaactactccttc
tacgtcctcgacaaccagaacttgcagcagctttgggattgggaccaccgtaacctgacc
atcaaagctgggaaaatgtattttgctttcaatcccaaattgtgcgtctccgaaatttac
cgcatggaagaagtgacggggaccaaaggacgccagagcaaaggagacataaataccaga
aacaatggagaacgagcctcctgtgaaagcgacgtcctgcacttcacctctacgaccaca
tggaagaatcgcatcatcatcacgtggcaccgttaccggccccctgactacagggatctc
atcagctttactgtctactacaaggaagcaccttttaaaaacgtcacggagtatgatggg
caggatgcctgtggctccaacagctggaatatggtagatgtggacctccctcccaacaag
gacgtcgagcctggcattttactgcacggactgaagccctggacgcagtatgcggtttat
gtcaaggcggtgaccctcaccatggtggagaatgaccacatccgtggggctaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttctgcg
tcaaactcctcttctcagctcattgtgaaatggaacccaccctctctgcccaacggtaac
ctcagttactacatcgtgaggtggcagcggcagccccaggacagttacctttaccgccac
aactactgctccaaagataaaatccccatcaggaagtatgctgatggcaccatcgatgtc
gaagaggtgacagagaatcccaagaccgaagtatgtggtggagagaaggggccttgctgt
gcctgccccaaaaccgaggccgagaagcaggctgagaaggaggaggccgagtaccgcaaa
gtgttcgagaatttcctgcacaactccatctttgtgcccagacctgaaaggaagcgtaga
gatgttacacaagtcaccaacaccaccatgtccagccgaagcaggaacaccacggtggtg
gacacctataatatcacagacccagaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtaatctctaacctccggccttttaccctgtaccgc
attgacatccacagctgcaatcatgaggctgagaagctgggctgcagtgcctccaacttt
gtttttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacctgg
gagtcaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatatggatcccaaatcgaggatcagcgagaatgtgta
tccagacaggagtacaggaagtatggaggtgccaagcttaaccggctcaacccggggaac
tatacagcccggatccaggccacttctctctctgggaatgggtcgtggacggatcctgtg
ttcttctatgtcccagccaaaataacgtatgaaaacttcatccatctgatcattgctctg
cccgttgctgtgctattgatagtgggagggttggttataatgctgtatgtcttccacagg
agaagaaataacagcaggctggggaatggagtgctgtatgcttccgtgaacccagaatac
ttcagtgctgccgatgtgtatgtacctgatgagtgggaggttgctcgagagaagatcacc
atgagccgagagctgggccagggctcatttgggatggtatatgaaggagttgccaagggt
gtggttaaagatgagcctgaaacaagggtggccattaaaacagtgaacgaggccgccagc
atgcgtgaaaggatcgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggtgtggtgtcccagggccagccgacgttggtcatcatggaa
ctgatgacacgaggggatctcaaaagttatctcaggtctctgaggccagaaatagagaat
aatccagtcctcgcacctccaagcctaagcaagatgatccagatggctggggagattgct
gatggcatggcatacctcaacgccaacaagtttgtccacagagaccttgctgccaggaac
tgcatggtggccgaagatttcacagtcaaaattggagatttcggtatgacaagagacatc
tatgagacagactattaccggaaaggaggcaaggggctgctgcctgtgcgctggatgtca
cctgagtctctcaaggatggagtcttcaccactcactctgacgtctggtcctttggggtc
gttctctgggagatcgccacgctggctgagcagccataccagggcttgtccaacgagcaa
gtccttcgcttcgttatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggacctggagccggagaacatg
gagagtgtccccctggacccgtcggcctcctcgtcgtcgctgcctctgcctgacagactc
tcaggacacaaggccgagaacggcccaggccctggcgtgctggtcctgcgagccagcttc
gatgagagacagccttacgcgcacatgaacgggggccgcaagaacgagcgggccttgcct
ctgccccagtcttcgacctgctga

DBGET integrated database retrieval system