KEGG   Oryx dammah (scimitar-horned oryx): 120852813
Entry
120852813         CDS       T07255                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic isoform X1
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
oda  Oryx dammah (scimitar-horned oryx)
Pathway
oda00670  One carbon pool by folate
oda01100  Metabolic pathways
oda01240  Biosynthesis of cofactors
oda04981  Folate transport and metabolism
Module
oda_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:oda00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    120852813 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    120852813 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oda04147]
    120852813 (MTHFD1)
Enzymes [BR:oda01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     120852813 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     120852813 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     120852813 (MTHFD1)
Exosome [BR:oda04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   120852813 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 120852813
NCBI-ProteinID: XP_040082205
LinkDB
Position
Unknown
AA seq 935 aa
MAPAEILNGKVVSAQIKERLKNQVIQMKEEVPGFIPGLAILQVGNRDDSNLYINVKLKAA
EEIGIKATHIKLPRTATESEVLKCITSLNEDLTVHGFIVQLPLDSENPINTETLVNAIAP
EKDVDGLNSISAGKLARGDLSNCFIPCTPKGCLELIKETGVQIAGRHAVVVGRSKIVGAP
MHDLLLWNHATVTTCHSKTVNLNEEISKGDILVVATGQPEMVKGEWIKPGAIVIDCGINY
VTDDTKPSGKKIVGDVAYKEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLENFKP
GKWIIEYNKLNLKTPVPSDIDISRSYKPKPIGNLAREIGLHTEEVELYGETKAKVRLSAL
ERLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLHQNVFACVRQPSQGPTFGI
KGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARMFHEETQTDKALFNRLV
PSVNGVRKFSDIQIRRLWRLGIEKTDPATLTDEEINRFARLDIDPETITWQRVLDTNDRF
LRKITIGQAPTEKGHSRTAQFDISVASEIMAVLALTSSLEDMRERLGKMVVASSKKGEPI
STEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVG
PKGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPTVTAGLPLP
KAYIEEDLELVGKGFSNLKKQIENARMFGVPVVVAVNAFKTDTEAELDLISHLAKEHGAF
DAVKCTHWAEGGKGALALAEAVQRAAVAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIE
LLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPELKGVPTGFILPIRDIRASVGAGFL
YPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF
NT seq 2808 nt   +upstreamnt  +downstreamnt
atggcgccggcggaaatcctgaacgggaaggtggtctccgcgcaaataaaggaaagactg
aagaaccaagtcattcagatgaaggaggaagtacctggtttcataccaggcctggcaatt
ttacaggttggcaacagagatgactctaatctttatataaatgtgaagttgaaggctgct
gaggagatcgggatcaaagccacgcacattaagttaccccgaacggccacggaatctgag
gtgttaaagtgcatcacgtcattgaacgaagacctcactgtgcatgggttcatagtgcag
ctacctttagattcagagaatcccattaacactgaaacattggtcaatgctattgccccc
gaaaaagatgtggacggactgaatagcatcagtgctggaaaacttgctagaggggacctt
agtaactgtttcatcccttgtacacccaaaggatgcttggaactcatcaaggagacaggg
gtgcaaattgctggaaggcacgctgtggtggttgggcgcagtaaaatcgttggtgcccca
atgcatgacttgcttctatggaaccatgccacagtgaccacctgccactccaagactgtg
aatctgaacgaggagataagtaaaggtgacatcctggtggttgcaactggtcaacctgaa
atggtgaaaggggagtggatcaaacctggggcgatagtcatcgactgtggaatcaattac
gtcacagatgatacaaaaccaagtgggaagaaaattgtgggtgatgtagcgtacaaggaa
gccaaggagagggcaagcttcatcacccctgttcctggtggcgtcgggcccatgacggtg
gcgatgctaatgcagagcacagtagagagtgcaaagcgcttcttggagaactttaagcca
gggaagtggatcatcgagtataacaaacttaacctgaagacacccgtgccaagtgacatt
gatatatcacggtcttacaagccaaagcccattggtaacctggctcgagaaattggtctg
cacactgaagaggtagaattgtacggtgaaaccaaggcaaaagttcggctctcagcgctg
gaacggctgaagcaccagcctgatgggaaatatgtggtggtaaccggaatcactccaaca
cccctgggagaggggaaaagcacaaccacgattggcctggtgcaggccctcggcgcccat
ctccatcagaatgtctttgcatgtgtgcgacagccttctcaggggcccacctttgggata
aaaggtggcgctgcaggcggtggctactctcaggtcattcctatggaagagtttaatctc
cacctcactggtgacatccatgccatcactgcagctaataaccttgtggccgcagccatc
gatgcccgtatgttccatgaagagacccagacagacaaggctctttttaatcgtttggtg
ccatcagtaaatggagtgagaaagttctctgatatccaaatccggaggttgtggagacta
ggcattgaaaagactgaccctgccacactgacagatgaagagataaacagatttgcaaga
ttggacattgatccagaaactataacttggcaaagagtgctggataccaatgatagattc
ctgaggaagatcacgatcggacaggctccaacggagaaggggcactcccggacggctcag
tttgatatctctgtggccagtgaaatcatggctgtcctggctctcaccagttctctagaa
gacatgagagagagactgggcaaaatggtggtggcgtccagcaaaaaaggggagcccatc
agtactgaggatctgggagtgagtggagcattgacggtccttatgaaggacgccatcaag
cccaatctcatgcagacattagagggcactccagtgtttgttcacgctgggccgtttgcc
aacatcgcacacgggaattcctccatcattgcagacaggattgcactcaagcttgtcggt
cccaaagggtttgtagtgactgaagcaggattcggagcagacattggaatggaaaagttc
ttcaacatcaaatgccggtattctggtctccgcccgcacgtggtggtgcttgtcgccact
gtcagggctctgaaaatgcacggaggcggccccacggttactgctggacttccgcttccc
aaggcctacatagaggaggacctggagctggttggaaaaggcttcagtaacttgaagaag
caaattgaaaatgccaggatgtttggtgtgccagtggtagtggccgtgaatgccttcaag
acagatacagaggctgagctggacctcatcagccacctcgccaaagaacatggtgctttt
gacgctgtgaagtgcactcactgggcagaagggggcaagggtgccctggcgctggctgag
gccgtccagagggcagctgtggcccccagcagcttccagctcctctacgacctcaagctc
ccagttgaggacaaaatcaggattattgcacagaagatctatggagctgacgacatcgaa
ttgctccctgaagcccagcacaaagcggaagtctacacaaagcagggctttgggaatctg
cccatctgcatggccaagacacacttgtccttgtctcacaacccagagctaaaaggcgtg
cccactggcttcatcctgcccattcgcgacatccgcgccagcgtcggggccggctttctg
taccctctggtgggaacgatgagcaccatgcctggactccctactcggccttgtttctat
gatattgatttggaccctgaaactgagcaggtgaatgggctgttctaa

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