KEGG   PATHWAY: cin00630
Entry
cin00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Ciona intestinalis (yellow sea squirt)
Class
Metabolism; Carbohydrate metabolism
Pathway map
cin00630  Glyoxylate and dicarboxylate metabolism
cin00630

Module
cin_M00621  Glycine cleavage system [PATH:cin00630]
cin_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:cin00630]
Other DBs
GO: 0046487 0043648
Organism
Ciona intestinalis (yellow sea squirt) [GN:cin]
Gene
100179555  acetyl-coenzyme A synthetase, cytoplasmic [KO:K01895] [EC:6.2.1.1]
104266550  acetyl-coenzyme A synthetase 2-like, mitochondrial [KO:K01895] [EC:6.2.1.1]
100187217  malate dehydrogenase, cytoplasmic-like isoform X2 [KO:K00025] [EC:1.1.1.37]
100178529  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
104266666  citrate synthase, mitochondrial-like [KO:K01647] [EC:2.3.3.1]
100186938  cytoplasmic aconitate hydratase [KO:K01681] [EC:4.2.1.3]
101243152  aconitate hydratase, mitochondrial-like [KO:K01681] [EC:4.2.1.3]
100177845  acetyl-CoA acetyltransferase, mitochondrial-like [KO:K00626] [EC:2.3.1.9]
100179335  methylmalonyl-CoA epimerase, mitochondrial-like [KO:K05606] [EC:5.1.99.1]
100177936  propionyl-CoA carboxylase alpha chain, mitochondrial [KO:K01965] [EC:6.4.1.3]
100177738  propionyl-CoA carboxylase beta chain, mitochondrial [KO:K01966] [EC:6.4.1.3 2.1.3.15]
100184488  methylmalonyl-CoA mutase, mitochondrial-like [KO:K01847] [EC:5.4.99.2]
100184957  hydroxyacid oxidase 1-like [KO:K11517] [EC:1.1.3.15]
100176957  hydroxyacid oxidase 1-like isoform X1 [KO:K11517] [EC:1.1.3.15]
100177352  catalase-like [KO:K03781] [EC:1.11.1.6]
100178763  glyoxylate reductase/hydroxypyruvate reductase [KO:K00049] [EC:1.1.1.79 1.1.1.81]
100175347  glycerol-3-phosphate phosphatase-like isoform X2 [KO:K19269] [EC:3.1.3.18 3.1.3.48]
100186158  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
100187164  serine hydroxymethyltransferase, cytosolic [KO:K00600] [EC:2.1.2.1]
100176513  serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
100176441  glycine dehydrogenase (decarboxylating), mitochondrial-like [KO:K00281] [EC:1.4.4.2]
100182526  aminomethyltransferase, mitochondrial-like [KO:K00605] [EC:2.1.2.10]
100180742  dihydrolipoyl dehydrogenase, mitochondrial [KO:K00382] [EC:1.8.1.4]
100184495  uncharacterized protein LOC100184495 [KO:K02437]
100175019  putative hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
100183164  glycerate kinase-like [KO:K11529] [EC:2.7.1.165]
100181036  4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
cin00010  Glycolysis / Gluconeogenesis
cin00020  Citrate cycle (TCA cycle)
cin00030  Pentose phosphate pathway
cin00053  Ascorbate and aldarate metabolism
cin00071  Fatty acid degradation
cin00230  Purine metabolism
cin00250  Alanine, aspartate and glutamate metabolism
cin00260  Glycine, serine and threonine metabolism
cin00620  Pyruvate metabolism
cin00750  Vitamin B6 metabolism
cin00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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