KEGG   Pseudopodoces humilis (Tibetan ground-tit): 102101641
Entry
102101641         CDS       T02921                                 
Symbol
MTHFD1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic isoform X1
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
phi  Pseudopodoces humilis (Tibetan ground-tit)
Pathway
phi00670  One carbon pool by folate
phi01100  Metabolic pathways
phi01240  Biosynthesis of cofactors
phi04981  Folate transport and metabolism
Module
phi_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:phi00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    102101641 (MTHFD1)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    102101641 (MTHFD1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:phi04147]
    102101641 (MTHFD1)
Enzymes [BR:phi01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     102101641 (MTHFD1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     102101641 (MTHFD1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     102101641 (MTHFD1)
Exosome [BR:phi04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   102101641 (MTHFD1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH DUF6507
Other DBs
NCBI-GeneID: 102101641
NCBI-ProteinID: XP_005520117
LinkDB
Position
Unknown
AA seq 935 aa
MAPAEILSGKIVSGQVRDRLKQQVVEMTEKFPGFRPGLAILQVGNRDDSNLYINMKLKAA
AEIGISANHIKLPNTATEADVLKCIASLNTDPAVHGFIVQLPLDSDKPINTEKITNAVAP
EKDVDGLSSINAGKLSRGDLGDCFIPCTPKGCMELIRQTGVQVAGKRAVVIGRSKIVGAP
MHDLLLWNNATVTTCHSKTSTLAEEVGKADILVVAAGRAEMVKGEWIKPGAIVIDCGINH
VPDSTKASGKRVVGDVAYSSAKEKASFITPVPGGVGPMTVAMLMQSTVESAQRFLEKFQP
GKWTIQYNQLTLKMPVPSDIEISQSCIPKPIDQVAKEVGLFPDEVELYGQTKAKIQLSVL
KRLQNQPDGKYVVVTGITPTPLGEGKSTTTVGLVQALGAHLRQNVFACVRQPSQGPTFGI
KGGAAGGGYCQVVPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQSDQALYNRLV
PSVNGVRKFSDIQIRRLQKLGINKTDPMALTKEEVNAFVRLDIDPGTITWQRVLDTNDRF
LRKITIGQSVTEKGFTRTAQFDITVSSEIMAVLALADGLDDMKKRFGRMVVASSKKGIPV
TADDLGVTGALAVLMKDAVKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVG
KDGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPAVTAGVPLP
KEYTEENLQLVAKGCSNLTKQIQNARMFGVPVVVAVNAFKTDTKAELALVVQHAKEAGAF
DAVECTHWAEGGKGALALARAVQRASQAPSNFRFLYNVELPVVDKIRLIAQQVYGARDIE
LLPEAQEKVALYTKQGFGNLPICMAKTHLSLSHDPEQKGAPTGFVLPIRDIRASVGAGFL
YPLVGTMSTMPGLPTRPCFYDIDLDPVSGAVNGLF
NT seq 2808 nt   +upstreamnt  +downstreamnt
atggcccccgccgagatcctcagtggcaagattgtctccggacaagtgagagacagacta
aagcagcaagttgttgagatgactgagaaatttccaggcttcagaccaggacttgccatt
ttgcaggttggaaatcgggatgattcaaacctctacattaacatgaagctgaaggctgct
gctgagattgggatcagtgccaatcacataaaattgccaaacacagcaacagaagctgat
gtgctcaagtgcattgcctctttgaatacagacccagctgttcatggctttatagtgcag
ctgccactcgactccgataaacccatcaacacagaaaaaataaccaatgctgtagcacct
gagaaggatgtggatggcttaagtagcatcaatgctgggaaactctctagaggagacctt
ggagactgctttattccatgtacgccaaagggatgcatggaacttatcaggcagacaggt
gtccaggtggcagggaaaagagccgtggtgatcggtcgcagtaagatcgtgggtgctccc
atgcatgacctgctgctctggaataacgcaacagtcaccacgtgccattccaagacctcc
accctggctgaggaggttggcaaagctgatatccttgtggttgcagctggtagagctgaa
atggtaaaaggtgaatggatcaagcctggtgcaatcgtaatagactgtggaattaaccat
gtgccagacagcacaaaggccagcggaaaaagagttgtgggagatgtggcatacagttca
gcaaaggaaaaagcttctttcatcaccccagttcctggtggtgttggacctatgactgtg
gccatgttaatgcagagcactgtggagagtgcacagcgttttctggagaagtttcagcct
ggaaaatggaccatccagtacaaccagcttaccctaaagatgcctgttccgagtgatatt
gaaatctcacagtcttgcatacccaagcccattgatcaagttgcaaaagaagttggcctt
ttccctgatgaggtggagctctatggccaaactaaagccaagattcagctctcagttctg
aaacgtctgcagaaccagccagatggcaaatatgtcgttgttactggaataactcccact
cccctgggagaggggaagagcaccaccactgttggccttgtccaagccttaggagcacac
cttcgccagaatgtctttgcctgtgttcggcagccttctcaggggccaacttttggcata
aaaggtggagctgcaggtggtggctattgtcaagttgtccccatggaagagtttaacctt
cacctcactggtgacatccatgccattactgcagccaacaacctggtcgctgctgctatt
gatgcacgtatattccacgagctgactcagtctgaccaggctctctacaaccgtttggtg
ccctctgtcaatggtgtcaggaagttctcagacattcagatccgaagactacagaaactg
ggcattaacaaaactgatcctatggctttgacaaaggaagaagtaaatgcatttgtgaga
ctggacattgacccaggcaccataacatggcaaagagtactggacacaaatgacagattc
cttaggaaaatcactattggacagtctgtaacagagaaaggcttcacacggacggctcag
tttgacatcacagtgagcagtgaaatcatggcagtcctagccctggctgatgggttggat
gatatgaaaaagcgatttggcagaatggtggtggcttccagcaaaaaaggaataccagtt
acagcagatgaccttggagtaactggagctctggctgtcttgatgaaggatgctgttaag
ccaaacctcatgcagacgctagagggaacaccagtgtttgttcatgctggaccttttgcc
aatattgcacatgggaattcctctgtgctggcagacaaaatagcattgaagcttgtgggt
aaagacggttttgttgttacagaagcaggatttggtgcagacataggcatggagaaattc
ttcaacattaagtgccgctattctggtctccggcctcatgtggtggtgttggttgctact
gtccgagctctgaaaatgcacgggggaggacctgcagtcactgctggggtacctctgcca
aaggaatacacagaagagaatcttcaactggtggcaaaaggctgcagcaacctaaccaag
caaatccagaatgcacggatgtttggtgtcccagtggttgtggctgtcaatgctttcaag
acagatacaaaggctgaactggcccttgtagtacaacatgcaaaggaggcaggagcattc
gatgctgtggagtgcactcactgggcagagggagggaaaggagccctggccctggcccga
gctgttcagagagcatcccaggcacctagcaacttcaggttcctctataatgtggagctg
cctgttgtagataagatcagacttattgcccagcaggtctacggggcaagagacattgag
ctccttcctgaagcacaggagaaagttgccctgtacaccaagcagggatttggaaacctg
ccaatctgcatggctaaaactcacttgtcattgtctcatgaccctgaacaaaaaggagca
cctacaggttttgttctgccaatccgagacattcgggccagcgttggggctgggttcttg
tatccactggtgggaacgatgagcacaatgccaggacttcctacaagaccctgcttctat
gatatagacctggacccagtgtcaggagcagtaaatgggctcttctga

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