KEGG   Panthera pardus (leopard): 109262704
Entry
109262704         CDS       T06062                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial isoform X1
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad00140  Steroid hormone biosynthesis
ppad01100  Metabolic pathways
ppad04913  Ovarian steroidogenesis
ppad04925  Aldosterone synthesis and secretion
ppad04927  Cortisol synthesis and secretion
ppad04934  Cushing syndrome
Module
ppad_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    109262704
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    109262704
   04925 Aldosterone synthesis and secretion
    109262704
   04927 Cortisol synthesis and secretion
    109262704
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    109262704
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ppad00199]
    109262704
Enzymes [BR:ppad01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     109262704
Cytochrome P450 [BR:ppad00199]
 Cytochrome P450, animal type
  CYP11 family
   109262704
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 109262704
NCBI-ProteinID: XP_019297020
Ensembl: ENSPPRG00000001983
LinkDB
Position
Unknown
AA seq 520 aa
MLAKGFPLRSVLVKGCQPLLNTSREGPGHPRVPTGEGAGISTQIPRPFSEIPSPGNNGWL
NLYNFWREMGSQKIHYHQLQNFQKYGPIYREKLGSMESVYIIDPEDVALLFKFEGPTPER
FSIPPWVAYHQHCQRPLGVLLKKSGAWKKDRLALNQEVMSPEAIKNFIPLLDPVSHDFVK
VLHRRIKLQGSGKFSGDISDDLFRFAFESITNVMFGERLGMLEEVVDPDAQRFIDAVYQM
FHTSVPMLNFPPDLFRLFKTKTWRDHVAAWDVIFNKAEAYTQNFYWDLRHKRDFNNYPCI
LQRLLRSHKLLFEDVKANITEMLAGGVDTTSMTLQWHLYEMARSLKVQEMLREEVRAARR
QAQGDISMMLQHVPLLKASIKETLRLHPISVTLQRYLENDLVLRNYMIPAKTLVQVSTYA
LGQDPTFFLNPGKFDPTRWLSNDKELIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILE
NFRVEMQHLSDVGTTFNLILMPDKPILLTFRPYSQDPPQV
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgctggccaaggggttccctcttcgctcagtcctggtcaaaggctgccagcccctcctg
aacacctcacgggagggtccagggcatcccagggtgcccactggggagggggctgggatc
tccactcagattccccgccccttcagcgagatcccctccccgggaaacaacggctggcta
aacttgtacaatttctggagggagatgggctcacagaaaatccactatcaccaactccag
aacttccagaagtatggccccatttacagggagaagctgggcagcatggagtcggtttat
atcatcgaccctgaagatgtggcccttctctttaagttcgagggtcccactccagaacga
ttttccatcccaccgtgggtggcctatcaccagcattgccagagacccctcggcgtcctg
ttgaagaagtcaggagcttggaagaaagaccgactggccctgaaccaggaggtgatgtct
ccagaggccataaagaacttcattcccctgctggacccagtgtctcacgactttgtgaaa
gtcctgcacaggcgcatcaagctgcagggctccggaaagttctcaggggacatcagtgac
gacctgtttcgctttgcctttgagtccatcaccaacgtcatgttcggggagcgcctgggg
atgctggaggaggtggtggaccctgacgcccagcggttcatcgacgctgtctaccagatg
ttccacaccagtgtccccatgctcaacttccccccagacctgttccgtctattcaagacc
aagacctggagggaccatgtggctgcgtgggatgtgattttcaataaagcggaggcatac
acccagaacttctactgggacctgaggcacaagagagatttcaacaattacccctgcatc
ctccaacgcctcctaagaagtcacaagctgctctttgaggatgtcaaggccaacataaca
gagatgttggcagggggtgtggacacgacgtccatgacattgcagtggcacttgtacgag
atggcacgcagcctgaaggtgcaggagatgctgcgggaggaggtccgggctgcccggcgc
caggcccagggagacatcagcatgatgttgcagcacgtcccgctcctcaaagccagcatc
aaggagacactgagactccaccccatctccgtgaccctgcagagataccttgaaaatgac
ttggttcttcgaaattacatgattcctgccaagacgttggtgcaggtgtccacctatgcc
ttgggccaagaccccaccttcttcctcaatccgggcaagtttgacccaacccgatggctg
agtaacgacaaggaactcatccacttccggaacctgggctttggctggggtgtgcggcag
tgtgtgggccggcggatcgctgagctcgagatgaccctcttcctcatccatattctggag
aacttcagagttgaaatgcaacatctcagtgatgtgggcaccacattcaacctcatcctg
atgcccgacaagcccatcctcctcaccttcaggccctacagccaggacccaccccaggtg
tga

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